243975-37-3

Basic information

• Product Name: (2R,5S,8S,11S,15S)-5-[3-({(E)-amino[(methylcarbamoyl)amino]methylidene}amino)propyl]-8-benzyl-2,7-dimethyl-3,6,9,13,17-pentaoxo-1,4,7,10,14-pentaazacycloheptadecane-11,15-dicarboxylic acid
• Synonyms: (2R,5S,8S,11S,15S)-8-benzyl-2,7-dimethyl-5-{3-[N''-(methylcarbamoyl)carbamimidamido]propyl}-3,6,9,13,17-pentaoxo-1,4,7,10,14-pentaazacycloheptadecane-11,15-dicarboxylic acid; 1,4,7,10,14-pentaazacycloheptadecane-11,15-dicarboxylic acid, 5-[3-[[(E)-amino[[(methylamino)carbonyl]imino]methyl]amino]propyl]-2,7-dimethyl-3,6,9,13,17-pentaoxo-8-(phenylmethyl)-, (2R,5S,8S,11S,15S)-
• CAS NO: 243975-37-3
• Molecular Formula: C₂₉H₄₁N₉O₁₀
• Molecular Weight: 675.6901
• Mol File: 243975-37-3.mol
• Article Data: 4

Chemical Properties

• Density: 1.49g/cm³
• Refractive Index: 1.657
• CAS DataBase Reference: (2R,5S,8S,11S,15S)-5-[3-({(E)-amino[(methylcarbamoyl)amino]methylidene}amino)propyl]-8-benzyl-2,7-dimethyl-3,6,9,13,17-pentaoxo-1,4,7,10,14-pentaazacycloheptadecane-11,15-dicarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,5S,8S,11S,15S)-5-[3-({(E)-amino[(methylcarbamoyl)amino]methylidene}amino)propyl]-8-benzyl-2,7-dimethyl-3,6,9,13,17-pentaoxo-1,4,7,10,14-pentaazacycloheptadecane-11,15-dicarboxylic acid(243975-37-3)
• EPA Substance Registry System: (2R,5S,8S,11S,15S)-5-[3-({(E)-amino[(methylcarbamoyl)amino]methylidene}amino)propyl]-8-benzyl-2,7-dimethyl-3,6,9,13,17-pentaoxo-1,4,7,10,14-pentaazacycloheptadecane-11,15-dicarboxylic acid(243975-37-3)

Safety Data

• Hazardous Substances Data: 243975-37-3(Hazardous Substances Data)

Usage

General Description

The chemical compound "(2R,5S,8S,11S,15S)-5-[3-({(E)-amino[(methylcarbamoyl)amino]methylidene}amino)propyl]-8-benzyl-2,7-dimethyl-3,6,9,13,17-pentaoxo-1,4,7,10,14-pentaazacycloheptadecane-11,15-dicarboxylic acid" is a peptide containing 22 amino acid residues. It has a complex structure with multiple functional groups, including carboxylic acids, a benzyl group, and an amino group. (2R,5S,8S,11S,15S)-5-[3-({(E)-amino[(methylcarbamoyl)amino]methylidene}amino)propyl]-8-benzyl-2,7-dimethyl-3,6,9,13,17-pentaoxo-1,4,7,10,14-pentaazacycloheptadecane-11,15-dicarboxylic acid likely has biological activity, potentially serving as a ligand for protein binding or other molecular interactions. Its detailed chemical structure and properties may make it suitable for various medicinal or research applications, depending on the specific biological activity it exhibits.

Upstream product

• 868840-76-0 (2R,5S,8S,11S,15S)-8-Benzyl-5-(3-guanidino-propyl)-2,7-dimethyl-3,6,9,13,17-pentaoxo-1,4,7,10,14-pentaaza-cycloheptadecane-11,15-dicarboxylic acid 
• 18342-66-0 2,5-dioxopyrrolidin-1-yl methylcarbamate 
• 1324007-50-2 C₁₀₇H₁₇₉N₉O₁₆ 
• 119831-72-0 Fmoc-Arg(Pbf)-OH 
• 129460-09-9 Fmoc-Asp-O-t-Bu 
• 868840-74-8 C₄₉H₇₄N₈O₁₃S 
• 868840-75-9 C₄₉H₇₂N₈O₁₂S 

Relevant articles and documents

Solution-phase total synthesis of the hydrophilic natural product argifin using 3,4,5-tris(octadecyloxy)benzyl tag

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Argifin; efficient solid phase total synthesis and evalution of analogues of acyclic peptide

An effective solid phase synthesis of Argifin, providing subsequent access to effective synthesis of analogues, was developed in 13% overall yield, as well as elucidating structure-activity relationships. The novel acyclic peptide 18b, prepared from a synthetic intermediate of Argifin, was found to be 70 times more potent as an inhibitor of Serratia marcescens chitinases B than Argifin itself.