24446-63-7

Upstream product

• 100-52-7 benzaldehyde 
• 101-97-3 Ethyl 2-phenylethanoate 
• 7647-01-0 hydrogenchloride 
• 64-17-5 ethanol 
• 501-65-5 diphenyl acetylene 
• 71-43-2 benzene 
• 123-91-1 1,4-dioxane 
• 100-39-0 benzyl bromide 
• 100-44-7 benzyl chloride 
• 17674-16-7 benzyl triflate 
• 10606-73-2 ethyl 2-chloro-2-phenylacetate 
• 1603-79-8 phenylglyoxylic acid ethyl ester 
• 1080-32-6 O,O-diethyl benzylphosphonate 
• 28557-00-8 phenylzinc chloride 

Downstream Products

• 5814-85-7 1,2-diphenylpropane 
• 3536-29-6 2,3-diphenyl-1-propanol 
• 94942-89-9 2,3-diphenylpropanoic acid 
• 103-29-7 1,1'-(1,2-ethanediyl)bisbenzene 
• 22835-64-9 α-phenylcinnamyl alcohol 
• 1228457-56-4 C₂₂H₂₇NOSi 
• 1228457-67-7 C₂₉H₃₇NO₄Si 
• 1228457-79-1 ethyl (E)-2-ethyl-3,4-dioxo-5,6-diphenylhex-5-enoate 
• 13702-35-7 (E)-2,3-diphenyl-propenal 

Relevant academic research and scientific papers

Palladium-catalyzed cross-coupling reaction of sulfoxonium ylides and benzyl bromides by carbene migratory insertion

A palladium-catalyzed cross-coupling reaction of sulfoxonium ylides and benzyl bromides has been developed, which has potential safety advantages over previous carbene coupling reactions using either diazo compounds or their in situ precursors. This reaction affords polysubstituted olefins, and features good substrate tolerance and is suitable for late-stage modification of biologically active molecules. Pd-carbene migratory insertion is supposed to be involved in this coupling reaction.

Novel method for using Carbene coupling reaction of palladium-catalyzed sulfur ylide and bromide to synthesize trisubstituted olefin

The invention relates to a novel method for using the Carbene coupling reaction of palladium-catalyzed sulfur ylide and bromide to synthesize trisubstituted olefin. A series of trisubstituted olefinscan be synthesized by the method. According to the method, safe, stable and easy-to-prepare sulfur ylide is adopted as a nucleophilic reagent for the Carbene coupling reaction, and the method has goodapplicability in the field of construction of substituted carbon-carbon double bonds.

Proline-based P,O ligand/iridium complexes as highly selective catalysts: Asymmetric hydrogenation of trisubstituted alkenes

P,O joins the mix: P,O ligands (L1) form efficient iridium catalysts for the asymmetric hydrogenation of olefins. The proline-derived ligands lead to high enantioselectivities with several classes of alkenes, most notably with α,β-unsaturated carboxylic e

Preparation of new 2,3-diphenylpropenoic acid esters - Good yields even for the more hindered Z isomers

The potassium salt of E- and Z-2,3-diphenylpropenoic acids prepaxed in situ could be esterified efficiently in DMSO with the appropriate alkyl halides at room temperature. In this way 10 previously undescribed esters of these acids were synthesised and characterised. Excellent yields were observed for most of the E isomers and the more hindered Z esters were also obtained in good yields, far better than those obtained applying the classical acid-catalysed esterification reaction.

Pd-SAPO-31, an efficient, heterogeneous catalyst for Heck reactions of aryl chlorides

Pd-SAPO-31 exhibits high activity for Heck reactions of aryl chlorides. These catalysts with activities superior to most known solid catalysts can be recovered and reused with negligible loss in activity.

Stereospecific Stille-coupling reaction of (Z)-1,2- bis(trimethylstannyl)ethenes with hypervalent iodonium salts

The Stille coupling of (Z)-1,2-bis(trimethylstannyl)ethenes with hypervalent iodonium salts (1 equiv) proceeded stereospecifically in the presence of PdCl2 (5 mol %) in DMF at room temperature to afford partially substituted (Z)-vinylstannanes under mild conditions. Alternatively, the use of 2 equivalents of hypervalent iodonium salts afforded tri-substituted alkenes.

New and efficient procedures for the synthesis of stereodefined 2-(hetero) aryl and 2-methyl substituted alkyl 2-alkenoates having very high stereoisomeric purity

Stereodefined 2-(hetero)aryl and 2-methyl substituted alkyl 2-alkenoates of general formulai and2 have been synthesized with a high degree of stereoselectivity as well as in good overall yields starting from alkyl 2-alkynoates,4.

Synthesis and Reactions of 2,3-Diaryl- and 2,3-Dialkylcyclopropenone Imines

A series of 2,3-diaryl- and 2,3-dialkylcyclopropenone iminium cations 3a-m and cyclopropenone imines 4a-i,l,m is prepared.The ring-opening reactions of imines 4a,f,i with some nucleophilic regents (water, alcohols, pyridine) give rise to products 5-7,10,11,16,17,20.