245759-64-2

Basic information

• Product Name: 4-Methoxy-alpha-methyl-N-(phenylmethyl)benzeneethanamine
• Synonyms: 4-methoxy-a-methyl-N-(phenylmethyl)benzeneethanamine;4-METHOXY-ALPHA-METHYL-N-(PHENYLMETHYL)BENZENEETHANAMINE;2-(N-Benzyl-N-(1-(4-methoxyphenyl)propan-2-yl)amino)-1-(3-amino-4-(benzyloxy)phenyl)ethanol
• CAS NO: 245759-64-2
• Molecular Formula: C17H21NO
• Molecular Weight: 255.35
• EINECS: 256-155-1
• Mol File: 245759-64-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 377.8 °C at 760 mmHg
• Flash Point: 160.3 °C
• Appearance: /
• Density: 1.025 g/cm³
• Vapor Pressure: 6.58E-06mmHg at 25°C
• Refractive Index: 1.553
• CAS DataBase Reference: 4-Methoxy-alpha-methyl-N-(phenylmethyl)benzeneethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Methoxy-alpha-methyl-N-(phenylmethyl)benzeneethanamine(245759-64-2)
• EPA Substance Registry System: 4-Methoxy-alpha-methyl-N-(phenylmethyl)benzeneethanamine(245759-64-2)

Safety Data

• Hazardous Substances Data: 245759-64-2(Hazardous Substances Data)

Usage

General Description

4-Methoxy-alpha-methyl-N-(phenylmethyl)benzeneethanamine, also known as 4-Me-MA, is a synthetic chemical compound that belongs to the amphetamine class of psychoactive substances. It is a potent central nervous system stimulant and a derivative of methamphetamine, with similar effects on the body and brain. 4-Me-MA is known to increase the release of dopamine and norepinephrine, leading to enhanced mood, alertness, and energy levels. It is also reported to have hallucinogenic and entactogenic effects, inducing feelings of euphoria and empathy. However, 4-Me-MA is not approved for medical use and is considered a controlled substance in many countries due to its potential for abuse and addiction. Long-term use of 4-Me-MA has been associated with various adverse health effects, including hypertension, heart problems, and psychological issues.

InChI:InChI=1/C17H21NO/c1-14(18-13-16-6-4-3-5-7-16)12-15-8-10-17(19-2)11-9-15/h3-11,14,18H,12-13H2,1-2H3

Upstream product

• 122-84-9 4-methoxybenzyl methyl ketone 
• 17199-29-0 (S)-Mandelic acid 
• 100-46-9 benzylamine 
• 611-71-2 (R)-Mandelic Acid 
• 43229-65-8 [2-(4-methoxyphenyl)-1-methylethyl](phenylmethyl)amine 
• 1049695-95-5 benzyl-[2-(4-methoxy-phenyl)-1-methyl-ethyl]-amine; hydrochloride 

Downstream Products

• 87833-61-2 (S,S)-formoterol fumarate 
• 67346-49-0 (S,S)-formoterol 
• 43229-80-7 N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-(4-methoxyphenyl)-1-methylethyl]-amino]ethyl]phenyl]formamide 
• 73573-87-2 (R,R)-formoterol 
• 188690-83-7 N-[5-[(1R)-Hydroxy-2-[[(1R)-methyl-2-(4-methoxyphenyl)ethyl](phenylmethyl)amino]ethyl]-2-(phenylmethoxy)phenyl]-formamide 
• 245759-65-3 (R,R)-3-nitro-α-[[[2-(4-methoxyphenyl)-1-methylethyl](phenylmethyl)amino]methyl]-4-(phenylmethoxy)-benzenemethanol 
• 289657-26-7 (R,R)-3-amino-α-[[[2-(4-methoxyphenyl)-1-methylethyl](phenyl methyl)amino]methyl]-4-(phenylmethoxy)-benzenemethanol 
• 1198769-18-4 (R)-4-benzyloxy-3-nitro-α-(N-benzyl-N-(1-methyl-2-p-methoxyphenylethyl)amino)acetophenone 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF ARFORMOTEROL OR SALT THEREOF

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PREPARATION OF (R,R)-FENOTEROL AND (R,R)- OR (R,S)-FENOTEROL ANALOGUES AND THEIR USE IN TREATING CONGESTIVE HEART FAILURE

This disclosure concerns the discovery of (R,R)- and (R,S)-fenoterol analogues which are highly effective at binding β2-adrenergic receptors. Exemplary chemical structures for these analogues are provided. Also provided are pharmaceutical compositions including the disclosed (R,R)-fenoterol and fenoterol analogues, and methods of using such compounds and compositions for the treatment of cardiac disorders such as congestive heart failure and pulmonary disorders such as asthma or chronic obstructive pulmonary disease.