24588-74-7

Basic information

• Product Name: 2-(4-nitrophenyl)-1,3-dithiane
• Synonyms: 1,3-Dithiane, 2- (4-nitrophenyl)-; 1,3-Dithiane, 2-(4-nitrophenyl)-
• CAS NO: 24588-74-7
• Molecular Formula: C₁₀H₁₁NO₂S₂
• Molecular Weight: 241.3298
• Mol File: 24588-74-7.mol
• Article Data: 53

Chemical Properties

• Boiling Point: 414.1°C at 760 mmHg
• Flash Point: 204.3°C
• Density: 1.33g/cm³
• Vapor Pressure: 1.09E-06mmHg at 25°C
• Refractive Index: 1.644
• CAS DataBase Reference: 2-(4-nitrophenyl)-1,3-dithiane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-nitrophenyl)-1,3-dithiane(24588-74-7)
• EPA Substance Registry System: 2-(4-nitrophenyl)-1,3-dithiane(24588-74-7)

Safety Data

• Hazardous Substances Data: 24588-74-7(Hazardous Substances Data)

Usage

General Description

2-(4-nitrophenyl)-1,3-dithiane is a chemical compound with the molecular formula C8H8N2O2S2. It is a dithiane derivative containing a nitrophenyl group. 2-(4-nitrophenyl)-1,3-dithiane is commonly used as a building block in organic synthesis, particularly in the formation of heterocyclic compounds. It is known for its ability to undergo various reactions such as alkylation, deprotonation, and oxidation, making it a versatile intermediate in the production of pharmaceuticals and agrochemicals. 2-(4-nitrophenyl)-1,3-dithiane is also used in the preparation of natural product analogs and complex molecules for research purposes. Due to its synthetic versatility, it is an important chemical for medicinal and materials chemistry.

Upstream product

• 505-23-7 1,3 dithiane 
• 98-95-3 nitrobenzene 
• 109-80-8 1.3-propanedithiol 
• 833-64-7 2-(p-nitrophenyl)-1,3-dioxane 
• 67-56-1 methanol 
• 555-16-8 4-nitrobenzaldehdye 
• 57529-04-1 2-chloro-1,3-dithiane 
• 6784-58-3 1-(1,3-dithian-2-ylidene)propan-2-one 
• 2403-53-4 2-(4-nitrophenyl)-1,3-dioxolane 
• 682360-46-9 2-(1,3-dithian-2-ylidene)-3-oxobutanoic acid 
• 628300-14-1 2,4-dichloro-3-(1,3-propylenedithio-methylene)-penta-1,4-diene 
• 2929-91-1 4-nitrobenzylidene diacetate 
• 59147-86-3 bis(p-nitrobenzylidene) pentaerythritol diacetal 
• 2403-62-5 p-nitrobenzaldehyde diethyl acetal 

Downstream Products

• 35531-59-0 2-deuterio-2-(4-nitrophenyl)-1,3-dithiane 
• 555-16-8 4-nitrobenzaldehdye 
• 111997-84-3 2-(4-Nitrophenyl)-1,3-dithian-2-ylium-tribromid 
• 881-67-4 4-nitrobenzaldehyde dimethyl acetal 
• 69278-14-4 2-(4-nitrophenyl)-1,3-dithiane 1-oxide 
• 94781-50-7 α-deuterio-4-nitro-benzaldehyde 
• 86201-73-2 4-(Nitro)thiobenzoesaeure-S-<3-<2-(4-nitrophenyl)-1,3-dithian-2-ylthio>propylester> 
• 84066-57-9 (E)-1-(p-nitrophenyl)-4-phenyl-3-buten-1-one N-tosylhydrazone 
• 84066-60-4 trans-1-phenyl-4-(p-nitrophenyl)-4-diazobut-1-ene 
• 84066-70-6 (E)-1-(p-nitrophenyl)-4-phenyl-3-buten-1-one 
• 84066-69-3 1-(p-nitrophenyl)-4-phenyl-3-buten-1,1-dithiane 

Relevant articles and documents

Direct synthesis of 1,3-dithiane substituted nitroarenes via vicarious nucleophilic substitution with 2-phenylthio- 1,3-dithiane

2-Phenylthio-l,3-dithiane underwent VNS with various nitroarenes to provide para-dithianyl nitroarenes regiospecifically in good to excellent yields. The resulting nitroaryl dithianes were readily unmasked to the corresponding aldehydes. (C) 2000 Elsevier

Ni-NiO heterojunctions: a versatile nanocatalyst for regioselective halogenation and oxidative esterification of aromatics

Herein, we report a facile method for the synthesis of Ni-NiO heterojunction nanoparticles, which we utilized for the nuclear halogenation reaction of phenol and substituted phenols usingN-bromosuccinimide (NBS). A remarkablepara-selectivity was achieved for the halogenated products under semi-aqueous conditions. Interestingly, blocking of thepara-position of phenol offeredortho-selective halogenation. In addition, the Ni-NiO nanoparticles catalyzed the oxidative esterification of carbonyl compounds with alcohol, diol or dithiol in the presence of a catalytic amount of NBS. It was observed that the aromatic carbonyls substituted with an electron-donating group favoured nuclear halogenation, whereas an electron-withdrawing group substitution in carbonyl compounds facilitated the oxidation reaction. In addition, the catalyst was magnetically separated and recycled 10 times. The tuned electronic structure at the Ni-NiO heterojunction controlled selectivity and activity as no suchpara-selectivity was observed with commercially available NiO or Ni nanoparticles.

An expedient carbon–sulfur bond formation explored through the cellulose sulfonic acid (CSA) catalyzed dithioacetal protection of carbonyl compounds

A facile carbon–sulfur bond formation was observed through the cellulose sulfonic acid (CSA) catalyzed dithioacetal protection of carbonyl compounds. In a preliminary study, the synthesis and characterization of functionalized bio-polymer, cellulose sulph