2461-75-8

Upstream product

• 22650-95-9 3,4-dihydro-1-methyl-5-<(2-oxo-2-phenylethyl)thio>-2H-pyrrolium bromide 
• 107-14-2 chloroacetonitrile 
• 22651-09-8 N-methyl-N-<<(2-oxo-2-phenylethyl)thio>methylene>methanaminium bromide 
• 106-95-6 allyl bromide 
• 70-11-1 α-bromoacetophenone 
• 75697-81-3 1-methyl-2-phenacylthioimidazoline 
• 2648-61-5 2,2-dichloroacetophenone 
• 530-48-3 1,1-Diphenylethylene 
• 2462-02-4 2-mercaptoacetophenone 
• 4356-69-8 1,1-bis-(4-methoxyphenyl)ethylene 
• 1712-70-5 1-chloro-4-(1-methylethenyl)-benzene 
• 2919-20-2 1,1-di(p-tolyl)ethylene 
• 98-83-9 isopropenylbenzene 
• 492-38-6 2-phenylacrylic acid 

Downstream Products

• 495-71-6 phenacylacetophenone 
• 3844-31-3 trans-thioindigo 
• 107619-79-4 2,2-diethyl-4-phenyl-2,5-dihydro-thiazole 
• 91642-80-7 ethyl-2 methyl-2 phenyl-4 Δ-3 thiazoline 
• 2461-80-5 diphenacyl sulfide 
• 94066-53-2 Diphenacyltrisulfid 
• 15441-14-2 bis-(1-benzoyl-3-oxo-3-phenyl-propyl)-sulfide 
• 15441-18-6 1,1'-Diphenyl-2,2'-thiobis(ethanone) 
• 17336-21-9 3-phenyl-1-thia-4-aza-spiro[4.5]dec-3-ene 
• 66692-87-3 2-ethyl-4-phenyl-2,5-dihydro-thiazole 
• 1260001-52-2 1,2-bis[(2-phenyl-1,3-dioxolan-2-yl)methyl]disulfane 
• 14006-54-3 3-chloro-1-benzothiophen-2-carbaldehyde 
• 357913-52-1 phenacyl methyl disulfide 
• 98-86-2 acetophenone 

Relevant academic research and scientific papers

Visible-Light-Mediated Additive-Free Decarboxylative Ketonization Reaction of Acrylic Acids: An Access to α-Thiocyanate Ketones

Visible-light-mediated additive-free decarboxylative functionalization of acrylic acids has been developed. The reaction uses inexpensive organic dye 9,10-dicyanoanthracene as a photocatalyst and uses the ubiquitous dioxygen as both an oxygen source and an oxidant. Through this mild and environmentally friendly method, a series of important α-thiocyanate ketones can be generated from easily available acrylic acids and ammonium thiocyanate. In addition, the facile transformation of product α-thiocyanate ketones makes this method have great potential for application in organic and pharmaceutical chemistry.

Thiol-Containing Metallo-β-Lactamase Inhibitors Resensitize Resistant Gram-Negative Bacteria to Meropenem

The prevalence of infections caused by metallo-β-lactamase (MBL) expressing Gram-negative bacteria has grown at an alarming rate in recent years. Despite the fact that MBLs can deactivate virtually all β-lactam antibiotics, there are as of yet no approved

TBAI-Catalyzed Reaction between N-Tosylhydrazones and Sulfur: A Procedure toward 1,2,3-Thiadiazole

A TBAI-catalyzed reaction between N-tosyl hydrazone and sulfur was developed, leading to 1,2,3-thiadiazoles in moderate to good yields. It represents a facile and practical procedure to access thiadiazole under metal-free conditions. This procedure serves

An efficient metal-free synthesis of organic disulfides from thiocyanates using poly-ionic resin hydroxide in aqueous medium

An efficient and metal-free method is described for the preparation of organic disulfides from alkyl and acyl methyl thiocyanates in the presence of poly-ionic resin hydroxide in aqueous medium. Further extension of this protocol has been tested using two different organyl thiocyanates to prepare unsymmetrical disulfides.

Regiocontrolled synthesis of ring-fused thieno[2,3-c]pyrazoles through 1,3-dipolar cycloaddition of nitrile imines with sulfur-based acetylenes

1,3-Dipolar cycloadditions of C-carboxymethyl-N-arylnitrile imines with substituted acetylenes bearing thiol or sulfone groups were studied. The sulfur controls the regiochemistry of the reaction, and this protocol was applied to the synthesis of ring-fus

The rapid and efficient synthesis of disulfides from alkyl and acyl halides

Various symmetrical dialkyl and diacyl disulfides are prepared easily in high yields from the corresponding alkyl and acyl halides under mild and nonaqueous conditions using N,N'-dibutyl-N,N,N',N'-tetramethyl- ethylenediammonium tetrahydroborate (BTMETB) or N,N'-dibenzyl-N,N,N',N'- tetramethylethylenediammonium tetrahydroborate (BZTMETB) and elemental sulfur. The quaternary diammonium borohydrides were easily prepared by treatment of the corresponding quaternary diammonium chloride or bromide with alkaline solution of sodium borohydride at room temperature.

Novel disulfides with antitumour efficacy and specificity

Some disulfides have previously been shown to possess antifungal and/or antileukaemic activity. Importantly, this cytotoxicity can be selective. We have previously shown that a subset of these compounds does not block the proliferative potential of normal

Sulfur containing compounds

This invention is directed to novel and known stufur containing compounds and pharmaceutically acceptable salts thereof that have utility as antifungals and as antiproliferative agents against mammalian cells, in particular cancer cells and most particularly leukemia-derived cells. The invention provides a method for synthesizing certain of the sulfur containing compounds that is more efficient than previously known methods.

Mn(III)-based reactions of alkenes and alkynes with thiols. An approach toward substituted 2,3-dihydro-1,4-oxathiins and simple route to (E)-vinyl sulfides

The first example using manganese(III) acetate in the reaction of 1,1- diarylethenes with α-mercaptoketones was examined. A mixture of the ethenes and α-mercaptoketones was treated with manganese(III) acetate in acetic acid, affording cycloaddition products in moderate yields, together with substituted products. The reaction may involve the formation of a carbonation and subsequent cyclization to give the substituted 2,3-dihydro-1,4-oxathiin 3. A similar reaction with thioglycolic acid gave 1,4-oxathiolan-2-one 7. While thiyl radicals easily formed by manganese(III) oxidation with ethanethiol or benzenethiol reacted with alkynes to give preferentially (E)- vinyl sulfides 10 in quantitative yields.