249507-22-0

Upstream product

• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 

Downstream Products

• 1585181-30-1 pyrrolidine-1,2-dicarboxylic acid (2S)-2-{(1S,3S,5S)-6-[(1S)-3-allyloxycarbonyl-1-[(triphenylmethylthio)methyl]propylcarbamoyl]-1-tert-butyl-3-methyl-5-(2,2,2-trichloroethoxycarbonyloxy)hex-1-yl}ester 1-(9H-fluoren-9-ylmethyl)ester 
• 1585180-89-7 pyrrolidine-1,2-dicarboxylic acid (2S)-2-{(1S,3S,5S)-6-[(1S)-3-allyloxycarbonyl-1-[(triphenylmethylthio)methyl]propylcarbamoyl]-1-tert-butyl-5-hydroxy-3-methylhex-1-yl}ester 1-(9H-fluoren-9-ylmethyl)ester 
• 878626-74-5 (2E)-(4S)-4-N-tert-butoxycarbonylamino-2-methyl-5-(triphenylmethylthio)-2-pentenoic acid allyl ester 
• 878626-79-0 (E)-(S)-4-tert-butoxycarbonylamino-2-methyl-5-(triphenylmethylthio)pentanoic acid ethyl ether 
• 1585181-32-3 pyrrolidine-1,2-dicarboxylic acid (2S)-2-{(1S,3S,5S)-6-[(1S)-3-allyloxycarbonyl-1-[(triphenylmethylthio)methyl]propylcarbamoyl]-1-tert-butyl-3,6-dimethyl-5-(2,2,2-trichloroethoxycarbonyloxy)-hept-1-yl}ester 1-(9H-fluoren-9-ylmethyl)ester 
• 1094435-87-6 C₂₉H₃₃NO₄S 
• 1333536-68-7 pyrrolidine-1,2-dicarboxylic acid (2S)-2-{(1S,3S,5S,6S)-6-[(1S)-3-allyloxycarbonyl-1-[(triphenylmethylthio)methyl]propylcarbamoyl]-1-tert-butyl-5-(2,2,2-trichloroethoxycarbonyloxy)-3-methylhept-1-yl}ester 1-(9H-fluoren-9-ylmethyl)ester 
• 1333536-82-5 (4S)-4-N-tert-butoxycarbonylamino-5-(triphenylmethylthio)-pentanoic acid allyl ester 
• 1094435-86-5 ethyl (S)-4-tert-butoxycarbonylamino-5-(triphenylmethylthio)pentanoate 
• 1333536-81-4 ethyl (S,E)-4-tert-butoxycarbonylamino-5-(triphenylmethylthio)-penta-2-enoate 
• 1333536-66-5 C₂₇H₂₉NO₂S 
• 175357-57-0 tert-butyl (S)-(1-oxo-3-(tritylthio)propan-2-yl)carbamate 
• 878626-72-3 1-[(9H-fluoren-9-yl)methyl] 2-[(3S,5S,7S,8S)-9-{[(S,E)-5-(allyloxy)-4-methyl-5-oxo-1-(tritylthio)pent-3-en-2-yl]amino}-2,2,5,8-tetramethyl-9-oxo-7-{[(2,2,2-trichloroethoxy)carbonyl]oxy}nonan-3-yl] (S)-pyrrolidine-1,2-dicarboxylate 
• 878626-89-2 (S)-Pyrrolidine-1,2-dicarboxylic acid 2-[(1S,3S,5S,6S)-6-((E)-(S)-3-allyloxycarbonyl-1-tritylsulfanylmethyl-but-2-enylcarbamoyl)-1-tert-butyl-5-hydroxy-3-methyl-heptyl] ester 1-(9H-fluoren-9-ylmethyl) ester 

Relevant academic research and scientific papers

Biologically Inspired Total Synthesis of Ulbactin F, an Iron-Binding Natural Product

Natural products from environmental microbiomes provide exquisite templates for elucidating biological activity in the search for new drugs. A recently discovered marine Brevibacillus sp. metabolite, ulbactin F, was found to inhibit tumor cell migration a

MACROCYCLIC THERAPEUTIC AGENTS, METHODS OF MANUFACTURE, AND METHODS OF TREATMENT

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Improved total synthesis and biological evaluation of potent apratoxin S4 based anticancer agents with differential stability and further enhanced activity

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Total synthesis of apratoxin A

We have achieved a total synthesis of apratoxin A in which thiazoline formation was accomplished from the moCys containing amide 4 using PPh 3(O)/Tf2O. Deprotection of the Troc and allyl ester in 17, coupling with tripeptide 3, and d