24967-79-1

Usage

Molecular Weight

330.80 g/mol

Structure

Three bromine atoms (tri-bromo) attached to positions 2, 4, and 6 of the phenol ring
One methoxy group (-OCH3) attached to position 3 of the phenol ring

Usage

Flame Retardant: Commonly employed to reduce flammability in various materials such as plastics, textiles, and electronics.
Preservative: Used in some personal care products for its preservative properties.
Intermediate: Serves as an intermediate compound in the synthesis of other organic compounds.

Toxicity

Considered toxic, posing potential health risks.

Environmental Concerns

Due to its toxicity and potential environmental impact, there is growing scrutiny of its usage.

Regulatory Attention

Ongoing efforts to develop safer alternatives to address health and environmental concerns associated with its use.

Upstream product

• 150-19-6 O-methylresorcine 
• 60-29-7 diethyl ether 
• 7726-95-6 bromine 
• 64-19-7 acetic acid 
• 673-22-3 2-Hydroxy-4-methoxybenzaldehyde 
• 16807-60-6 3-methoxycyclohex-2-en-1-one 
• 66693-87-6 4,6-dibromo-3-methoxyphenol 

Downstream Products

• 66693-87-6 4,6-dibromo-3-methoxyphenol 
• 156570-79-5 2,3,5-tribromo-6-methoxy[1,4]benzoquinone 
• 757232-66-9 2,4-dibromo-3-methoxy-6-nitro-phenol 
• 24988-36-1 4,6-dibromo-1,3-dimethoxybenzene 
• 2437-49-2 2,4,6-tribromoresorcinol 

Relevant academic research and scientific papers

Practical regioselective halogenation of vinylogous esters: Synthesis of differentiated mono-haloresorcinols and polyhalogenated resorcinols

A practical and efficient method for the direct, regioselective conversion of vinylogous esters to haloresorcinols is reported. Control of the reaction conditions enables synthesis of either the 4- or 6-haloresorcinol isomers from a common precursor with excellent regiocontrol and high yield. The generality and functional group tolerance of this novel protocol is demonstrated. The utility of this methodology to access polyhaloresorcinols is also reported. These methods create useful functionalized building blocks for further synthetic applications.

Pyridinium hydrobromide perbromide induces ipsobromodeformylation in o-hydroxy and o-methoxy substituted aromatic aldehydes

The reaction of o-hydroxy and o-methoxy substituted aromatic aldehydes with PHPB in pyridine gives aromatic bromination products including those arising from ipsobromodeformylation.

Bromination of Phenols by Use of Benzyltrimethylammonium Tribromide

The reaction of phenols with benzyltrimethylammonium tribromide in dichloromethane-methanol for 1 h at room temperature gave polybromophenols in good yields.