25017-78-1Relevant articles and documents
A study of two geometric isomers of 1,1′-bi-3-cyanocyclohex-2-enylidene
Wang, Yonghui,Doering,Staples, Richard J.
, p. 977 - 982 (1999)
The preparation, separation, crystal structure and 1H NMR spectra are reported for the two geometrical isomers of 1,1′-bi-3-cyanocyclohex-2-enylidene. The E-isomer crystallized as thin plates in the monoclinic space group P21,/n with a = 5.3980(5), b = 7.0757(7), c = 15.300(2) A, β = 94.571(2)°, and Z = 2. The structure has symmetry C2h. The Z-isomer crystallized as needles in the triclinic space group PT with a = 7.0790(6), b = 11.3155(9), c = 15.386(1) A, α = 104.943° β= 90.164(2)°, γ = 99.494(2)°, and Z = 4. The compound crystallized with two molecules per asymmetric unit. In C6D6,1H NMR signals of the 2-vinyl protons appear almost identical. However, in a mixture of C6D6 and pyridine-d5, the 2-vinyl protons can be distinguished. The structures compare favorably with MM2 calculations.
Corresponding amine nitrile and method of manufacturing thereof
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Paragraph 0143-0145; 0150; 0151; 0162; 0184; 0217; 0228, (2017/10/22)
The invention relates to a manufacturing method of nitrile. Compared with the prior art, the manufacturing method has the characteristics of significantly reduced using amount of an ammonia source, low environmental pressure, low energy consumption, low production cost, high purity and yield of a nitrile product and the like, and nitrile with a more complex structure can be obtained. The invention also relates to a method for manufacturing corresponding amine from nitrile.
Fluorous bispidine: A bifunctional reagent for copper-catalyzed oxidation and knoevenagel condensation reactions in water
Ang, Wei Jie,Chng, Yong Sheng,Lam, Yulin
, p. 81415 - 81428 (2015/10/06)
Fluorous bispidine-type ligands have been developed to facilitate its recovery and reusability and to demonstrate its bifunctional property as a ligand and base in copper-catalyzed aerobic oxidation, the Knoevenagel condensation and tandem oxidation/Knoevenagel condensation in water under mild conditions. Application of the fluorous ligand was also extended to the surfactant-free copper-catalyzed allylic and benzylic sp3 C-H oxidation reaction in water. The fluorous ligands could be recovered using F-SPE with recovery ranging from 91-97% and could be reused five times with little loss of activity.
Preparation of 3-oxocyclohex-1-ene-1-carbonitrile
Lujan-Montelongo, Jesus Armando,Fleming, Fraser F.
, p. 229 - 239 (2014/04/03)
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