25039-25-2

Upstream product

• 62-53-3 aniline 
• 3306-07-8 1-benzoyl-2-chloroethene 
• 41125-10-4 benzoylacetaldehyde sodium salt 
• 142-04-1 aniline hydrochloride 
• 1131-80-2 (E)-3-(N,N-dimethylamino)-1-phenyl-2-propen-1-one 
• 4187-87-5 1-Phenyl-2-propyn-1-ol 
• 98-86-2 acetophenone 
• 1201-93-0 1-phenyl-3-dimethylaminoprop-2-enone 
• 3623-15-2 phenyl propargyl ketone 
• 100-52-7 benzaldehyde 
• 93-55-0 1-phenyl-propan-1-one 
• 15397-33-8 3-Oxo-3-phenylpropanal 
• 102-01-2 N-phenylacetoacetamide 

Downstream Products

• 92126-72-2 6-phenyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile 
• 5220-59-7 1-(2-methyl-6-phenylpyridin-3-yl)ethan-1-one 
• 1166821-21-1 phenyl(4-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methanone 
• 1166821-25-5 (4-(4-chlorophenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)(phenyl)methanone 
• 1166821-26-6 (4-(4-bromophenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)(phenyl)methanone 
• 1166821-22-2 4-(4-methylphenyl)-5-phenylmethanone-yl-3,4-dihydropyrimidine-2(1H)-thione 
• 1434475-14-5 phenyl(1,4,6,6-tetraphenyl-1,6-dihydropyridin-3-yl)methanone 
• 1434475-17-8 (6-(4-chlorophenyl)-6-methyl-1,4-diphenyl-1,6-dihydropyridin-3-yl)(phenyl)methanone 
• 1434475-20-3 (6-cyclopropyl-1,4,6-triphenyl-1,6-dihydropyridin-3-yl)(phenyl)methanone 
• 1434475-23-6 C₃₁H₂₄FNO 
• 1434475-26-9 (6-methyl-1,6-diphenyl-4-(p-tolyl)-1,6-dihydropyridin-3-yl)(phenyl)methanone 
• 1434475-29-2 (4-butyl-6-methyl-1,6-diphenyl-1,6-dihydropyridin-3-yl)(phenyl)methanone 
• 1434475-38-3 (E)-(4-butylidene-6-methyl-1,6-diphenyl-1,4,5,6-tetrahydropyridin-3-yl)(phenyl)methanone 
• 1434475-32-7 (6-methyl-4-phenethyl-1,6-diphenyl-1,6-dihydropyridin-3-yl)(phenyl)methanone 

Relevant academic research and scientific papers

X-RAY DIFFRACTION STUDY OF 1-BENZOYL-2-(N-ACETYL-N-PHENYLAMINO)ETHYLENE

An X-ray diffraction study has been carried out of the photochemically inactive 1-benzoyl-2-(N-acetyl-N-phenylamino)ethylene C17H15NO2 (diffractometer, λCuKα radiation, 1110 independent reflections, direct method, full-matrix least-squares method, R = 0.037).The crystals are monoclinic, a = 8.268(8), b = 9.703(4), c = 17.473(6) Angstroem, γ = 83 deg 20'(3'), space group P21/b, Z = 4.The possible reasons for the photostability of the compound related to the absence of steric strains in the molecule are discussed.

Silver-mediated aminophosphinoylation of propargyl alcohols with aromatic amines and H-phosphine oxides leading to α-aminophosphine oxides

A new silver mediated aminophosphinoylation of propargyl alcohols with aromatic amines and H-phosphine oxides for the construction of α-aminophosphine oxides has been developed. The C[sbnd]N and C[sbnd]P bond could be efficiently formed in one pot operati

Fe-Catalyzed enaminone synthesis from ketones and amines

We have developed an iron-catalyzed direct olefination for enaminone synthesis, with saturated ketones as a source of olefins. This direct ketone β-functionalization reaction has readily available starting materials and a wide range of substrates and requires mild reaction conditions.

Silver(i)/base-promoted propargyl alcohol-controlled regio- or stereoselective synthesis of furan-3-carboxamides and (Z)-enaminones

A novel and facile regioselective synthesis of furan-3-carboxamides by a silver(i)/base-promoted reaction of propargyl alcohol with 3-oxo amides has been demonstrated. This one-pot protocol provides a rapid synthetic approach to diverse trisubstituted furan-3-carboxamides via cascade nucleophilic addition, intramolecular cyclization, elimination, and isomerization reactions. Employing a substituted propargyl alcohol, (Z)-enaminones have been obtained with high stereoselectivities by a Ag2CO3-promoted reaction starting from 3-oxo amides via C-N bond cleavage.

COMPOUNDS AND METHODS FOR HEMATOPOIETIC REGENERATION

The invention relates to compounds that promote hematopoietic regeneration. The invention further relates to methods of promoting hematopoietic regeneration using the novel compounds of the invention.

Conjugate Addition of 3-Buytn-2-one to Anilines in Ethanol: Alkene Geometric Insights through in Situ FTIR Monitoring

A convenient, mild and effective conjugate addition of 3-butyn-2-one to a variety of anilines in ethanol is reported. The reaction was monitored and characterized through in situ FTIR, and the dynamics of the facile E/Z alkene geometry interconversion of the resultant aniline-derived enaminones was explored through NMR, FTIR and X-ray crystallography. A straightforward purification protocol that employs direct Kugelrohr distillation was identified, and the method was further extended to other amines and ynones, allowing rapid access to these interesting compounds.

Water-promoted synthesis of enaminones: Mechanism investigation and application in multicomponent reactions

Highly stereoselective synthesis of Z-enaminones bearing reactive secondary amino group has been successfully performed in water using tertiary amino group functionalized enaminones under ambient conditions. An interesting promotion effect of water on the

KHSO4 assisted Michael addition-elimination reactions of formylated acetophenones in water: A facile general green synthetic route to 3-(alkyl/aralkyl/aryl)amino-1-arylprop-2-en-1-ones

A facile general green synthetic route to 3-(alkyl/aralkyl/aryl)amino-1- arylprop-2-en-1-ones in excellent yields has been developed by reacting formylated acetophenones with primary amines assisted by KHSO4 in water.

Ruthenium complexes of electronically coupled cyclopentadienone ligands - Catalysts for transformations of propargyl alcohols

A series of donor- and acceptor-substituted ruthenium cyclopentadienone complexes were synthesized and their catalytic activities towards propargyl alcohols focused on amination reactions have been investigated. It is shown that the substituents of the cyclopentadienone ligand determine the mode of activation of propargyl alcohols by these complexes leading to different central intermediates in catalytic cycles. Catalytic transformations of propargyl alcohols to α- or β-amino ketones, enamino ketones, α,β-unsaturated imines, ketones, alkenes and conjugated enynes could be achieved. Wiley-VCH Verlag GmbH & Co. KGaA, 2007.

Ruthenium-catalyzed enaminoketone formation from propargyl alcohols

Monomeric ruthenium(0) complexes containing electronically coupled dienone ligands were found to catalyze the formation of enaminoketones from propargyl alcohols. Georg Thieme Verlag Stuttgart.