250656-24-7Relevant articles and documents
SSAO INHIBITOR
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Paragraph 0136-0138, (2020/04/02)
The present invention provides an SSAO inhibitor and an application thereof in preparing a drug for treating a disease related to SSAO. In particular, the present invention provides a compound shown in formula (IV) and a pharmaceutically acceptable salt thereof.
Transition Metal-catalyzed Protocarboxylation of alpha-Halo-acrylic Acid Derivatives
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Paragraph 0339-0341, (2018/09/23)
The present invention relates to a method for the synthesis of a halo olefin of formula (I) wherein Hal, R1, R2, R3, R4, X and Y are as defined herein, or a salt thereof.
Amidation of aryl halides with isocyanides using a polymer-supported palladium-n-heterocyclic carbene complex as an efficient, phosphine-free and heterogeneous recyclable catalyst
Khairnar, Bhikan J.,Bhanage, Bhalchandra M.
supporting information, p. 1236 - 1242 (2014/05/06)
The amidation of aryl halides with alkyl/aryl isocyanides to give the corresponding amides using polymer-supported palladium-N-heterocyclic carbene complex (PS-Pd-NHC) as an efficient heterogeneous recyclable catalyst is described. The catalytic system was optimized with respect to various reaction parameters giving excellent yields of the desired products. The catalyst can be easily separated by a simple filtration process and recycled further for up to four consecutive recycle without any loss of activity and selectivity. The protocol is advantageous due to the ease in handling of the catalyst, simple workup procedure, phosphine-free, and effective catalyst recyclability. Georg Thieme Verlag Stuttgart New York.