25099-77-8Relevant academic research and scientific papers
Central-metal exchange, improved catalytic activity, photoluminescence properties of a new family of d10 coordination polymers based on the 5,5′-(1: H -2,3,5-triazole-1,4-diyl)diisophthalic acid ligand
Wang, Huarui,Huang, Chao,Han, Yanbing,Shao, Zhichao,Hou, Hongwei,Fan, Yaoting
, p. 7776 - 7785 (2016)
The rigid and planar tetracarboxylic acid 5,5′-(1H-2,3,5-triazole-1,4-diyl)diisophthalic acid (H4L), incorporating a triazole group, has been used with no or different pyridine-based linkers to construct a family of d10 coordination
Visible Light-Promoted Aryl Azoline Formation over Mesoporous Organosilica as Heterogeneous Photocatalyst
Wei, Wenxin,Li, Run,Huber, Niklas,Kizilsavas, G?nül,Ferguson, Calum T. J.,Landfester, Katharina,Zhang, Kai A. I.
, p. 3410 - 3413 (2021/05/29)
N-heterocyclic compounds demonstrate wide applications ranging from natural compound production to coordination chemistry. Usually, the synthesis of N-heterocyclic compounds is conducted under thermal conditions, mostly by Lewis acids or metal-containing compounds as molecular catalysts. Here, we report a photocatalytic route for aryl azoline formation by mesoporous organosilica as visible light-active and heterogeneous photocatalyst. Via formation of aromatic aldehydes with various amines, 2-phenyl-2-imidazoline, 2-phenyl-2-oxazoline, 2-phenyl-2-thiazoline and their derivatives could be formed with high conversion and selectivity. Additionally, the organosilica photocatalyst showed high stability and reusability.
A cobalt coordination polymer from bulk to nanoscale crystals as heterogeneous catalysts for tandem reactions
Han, Suzhen,Wang, Wenjie,Lu, Guizhen,Wang, Di,Zhang, Ying-Ying,Shao, Zhichao,Huang, Chao
, (2021/04/23)
Constructing nanoscale coordination polymers (CPs) with different micro- or nanoscale morphologies and sizes is crucial for the functionalization of CPs-based heterogeneous catalysts. Herein, surfactant polyvinylpyrrolidone (PVP), surface-supported frameworks (filter paper or Ni foam), and Co-based CPs (1), [Co2(pdpa)(py)4(H2O)]n (H4pdpa ?= ?5,5’-(pentane-1,2-diyl)-bis(oxy)diisophthalic; py ?= ?pyridine)) were employed to develop highly ordered micro- or nanoscale CPs, achieving microscale 1a (without surface-supported framework) and nanoscale 1b-c (filter paper and Ni foam as surface-supported frameworks for 1b and 1c, respectively). Furthermore, the catalytic performance of nanoscale 1c with spheric particles for the tandem conversion reactions of aromatic nitriles and diamines into imidazoline or tetrahydropyrimidine frameworks was much more prominent than that of large scale 1, microscale 1a, and nanoscale 1b because of the easily accessible catalytic active sites in the nanoscale spheric particles, which offered a functionalizable platform for the tandem reactions by minimizing the diffusion distance but did little for their activity.
1, 4, 5, 6-tetrahydro-pyrimidine derivative synthesis method
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Paragraph 0023-0025, (2017/01/26)
The invention discloses a novel method for synthesizing a 1,4,5,6-tetrahydropyrimidine derivative. The derivative is prepared through reaction between 2-aryl-substituted nitrile and 1,3-diaminopropane with copper cinnamate as a catalyst. The novel method has the advantages that the synthesis technology is simple and does not have strict requirements on reaction conditions, and the catalyst is cheap and can be reutilized, thereby facilitating actual production; the yield can reach 60%-90%.
Metal-free one-pot synthesis of 1,3-diazaheterocyclic compounds via I2-mediated oxidative C-N bond formation
Tian, Xianhai,Song, Lina,Li, Ertong,Wang, Qiang,Yu, Wenquan,Chang, Junbiao
, p. 62194 - 62201 (2015/08/03)
A one-pot I2-mediated annulation reaction of substrates containing diamino groups and aldehydes has been developed via oxidative C-N bond formation. This general and environmentally benign synthetic approach provides facile access to a variety of 1,3-diazaheterocyclic compounds, including quinazolinones, benzimidazoles, and cyclic amidines.
Solvent templates induced porous metal-organic materials: Conformational isomerism and catalytic activity
Ding, Ran,Huang, Chao,Lu, Jingjing,Wang, Junning,Song, Chuanjun,Wu, Jie,Hou, Hongwei,Fan, Yaoting
, p. 1405 - 1413 (2015/05/27)
Solvent templates induced Co-based metal-organic materials; conformational isomers {[Co2(pdpa)(CH3CN)(H2O)3]·CH3OH·H2O}n (1) and {[Co2(pdpa)(CH3CN)(H2O)3]}n (2) and {[Co5(pdpa)2(μ3-OH)2(H2O)6]·2H2O}n (3) [H4pdpa = 5,5′-(pentane-1,2-diyl)-bis(oxy)diisophthalic acid] were synthesized under the same solvothermal conditions except with different concentrations of cyclic ethers (1,4-dioxane or tetrahydrofuran) as structure-directing agents. Structural transformations from a three-dimensional (3D) framework of 1 containing channels with dimensions of μ6 ? × 6 ? to a two-dimensional layer structure of 2 consisting of large open channels with a size of μ15 ? × 8 ? and then to a 3D nonporous framework of 3, resulting from the different concentrations of cyclic ethers, were observed. The anion-π interactions between electron-efficient oxygen atoms of cyclic ethers and electron-deficient dicarboxylic acid aromatic cores in H4pdpa imported into the synthetic process accounted for the conformational change of the ligand H4pdpa and the following structural variations. A systematic investigation was conducted to explore how different concentrations of structure-directing agents affected the frameworks of resultant metal-organic frameworks. Furthermore, 1-3 were shown to be available heterogeneous catalysts for the synthesis of 2-imidazoline and 1,4,5,6-tetrahydropyrimidine derivatives by the cascade cycloaddition reactions of aromatic nitriles with diamines. The results showed that the catalytic activity of 2 was much higher than that of 1 and 3, because of its unique structural features, including accessible catalytic sites and suitable channel size and shape. In addition, a plausible mechanism for these catalytic reactions was proposed, and the reactivity-structure relationship was further clarified.
Efficient and benign one-pot conversion of n-tosyl-1,4,5,6- tetrahydropyrimidines to pyrimidines via tandem β-elimination and aromatization
Trieu, Tien Ha,Dong, Jing,Shi, Xiao-Xin,Lu, Xia,Zhang, Qiang
, p. 3141 - 3152 (2014/01/06)
An efficient, mild, benign, and practical method for one-pot conversion of N-tosyl-1,4,5,6-tetrahydropyrimidines into pyrimidines is discussed in detail. In this method, N-tosyl-1,4,5,6-tetrahydropyrimidines are first prepared via N-tosylation of tetrahyd
Cyclodehydration of N -(aminoalkyl)benzamides under mild conditions with a hendrickson reagent analogue
Loughlin, Wendy A.,Jenkins, Ian D.,Petersson, Maria J.
, p. 7356 - 7361 (2013/08/23)
Methods for the cyclodehydration of N-(aminoalkyl)benzamides are few and employ harsh reaction conditions. We have found that the easily prepared phosphonium anhydrides 1 (Hendrickson reagent) or 2 can be used for cyclodehydration of N-(aminoalkyl)benzamides under very mild conditions (room temperature) to produce five-, six-, and seven-membered cyclic amidines. Good yields are obtained by employing a temporary trityl group protection strategy. Cyclic analogue 2 can be used when the product cyclic amidine is organic-soluble, thus producing water-soluble byproducts.
Microwave-assisted cascade cycloaddition for C-N bond formation: An approach to the construction of 1,4,5,6-tetrahydropyrimidine and 2-imidazoline derivatives
An, Shujuan,Yin, Bing,Liu, Ping,Li, Xiangnan,Li, Chen,Li, Jianli,Shi, Zhen
, p. 2525 - 2532 (2013/09/24)
An efficient strategy for the synthesis of various 1,4,5,6- tetrahydropyrimidine and 2-imidazoline derivatives has been reported. The reactions proceeded from nitriles with ethylenediamine or 1,3-diaminopropane via cascade cycloaddition in the presence of CuL2 (L = 2-hydroxy-2-phenylacetate) to afford the corresponding 1,4,5,6- tetrahydropyrimidine or 2-imidazoline derivatives under reflux conditions or microwave irradiation in excellent yields.
Palladium-catalyzed multicomponent synthesis of 2-aryl-2-imidazolines from aryl halides and diamines
Geden, Joanna V.,Pancholi, Alpa K.,Shipman, Michael
, p. 4158 - 4164 (2013/05/22)
An efficient palladium-catalyzed three-component reaction that combines aryl halides, isocyanides, and diamines provides access to 2-aryl-2-imidazolines in yields up to 96%. Through variation of the diamine component, the reaction can be extended to the s
