251658-77-2Relevant academic research and scientific papers
Practical synthesis of 1,3-diaryl-5-alkylpyrazoles by a highly regioselective N-arylation of 3,5-disubstituted pyrazoles with 4- fluoronitrobenzene
Wang, Xiao-Jun,Tan, Jonathan,Grozinger, Karl,Betageri, Raj,Kirrane, Tom,Proudfoot, John R.
, p. 5321 - 5324 (2000)
3-Aryl-5-alkylpyrazoles undergo a highly regioselective arylation on N-1 atom with 4-fluoronitrobenzene in the presence of base to yield the corresponding 1-(4-nitrophenyl)pyrazoles. (C) 2000 Elsevier Science Ltd.
Substituted 1-(4-aminophenyl)pyrazoles and their use as anti-inflammatory agents
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, (2008/06/13)
1-(4-aminophenyl)pyrazoles optionally substituted on the 3- and 5-positions of the pyrazole ring and on the amino group at the 4-position of the phenyl ring are disclosed and described, which pyrazoles inhibit IL-2 production in T-lymphocytes.
