25174-15-6

Upstream product

• 41125-10-4 benzoylacetaldehyde sodium salt 
• 20265-97-8 p-anisidine hydrochloride 
• 104-94-9 4-methoxy-aniline 
• 3623-15-2 phenyl propargyl ketone 
• 5437-98-9 4'-methoxyacetoacetanilide 
• 4187-87-5 1-Phenyl-2-propyn-1-ol 
• 93-55-0 1-phenyl-propan-1-one 
• 89530-34-7 1-phenyl-3-trimethylsilylprop-2-yn-1-ol 
• 98-86-2 acetophenone 
• 1201-93-0 1-phenyl-3-dimethylaminoprop-2-enone 

Downstream Products

• 22214-26-2 cis-3-p-Anisidino-1-phenyl-propen-⁽²⁾-thion-⁽¹⁾ 
• 1242517-16-3 (1-(4-methoxyphenyl)-4-(thiophen-2-yl)-1,4-dihydropyridine-3,5-diyl)bis(phenylmethanone) 
• 1242517-14-1 (1-(4-methoxyphenyl)-4-p-tolyl-1,4-dihydropyridine-3,5-diyl)bis(phenylmethanone) 
• 1242517-12-9 (4-(4-chlorophenyl)-1-(4-methoxyphenyl)-1,4-dihydropyridine-3,5-diyl)bis(phenylmethanone) 
• 5455-87-8 4-methoxy-N-(4-nitrobenzylidene)aniline 
• 1242517-05-0 (1-(4-methoxyphenyl)-4-(4-nitrophenyl)-1,4-dihydropyridine-3,5-diyl)bis(phenylmethanone) 
• 1242517-13-0 (1-(4-methoxyphenyl)-4-phenyl-1,4-dihydropyridine-3,5-diyl)bis(phenylmethanone) 
• 1242517-15-2 (1,4-bis(4-methoxyphenyl)-1,4-dihydropyridine-3,5-diyl)bis(phenylmethanone) 
• 1434474-99-3 (1-(4-methoxyphenyl)-6-methyl-4,6-diphenyl-1,6-dihydropyridin-3-yl)(phenyl)methanone 

Relevant academic research and scientific papers

A Metal- and Azide-Free Multicomponent Assembly toward Regioselective Construction of 1,5-Disubstituted 1,2,3-Triazoles

The construction of 1,5-disubstituted 1,2,3-triazoles has been effected through the cascade dual C-N bond formation, N-N bond formation and an acyl migration-based C-C bond formation via the three-component reactions of enaminones, tosylhydrazine and prim

Hydrogen-Borrowing Amination of Secondary Alcohols Promoted by a (Cyclopentadienone)iron Complex

Thanks to a highly active catalyst, the scope of the (cyclopentadienone)iron complex-promoted 'hydrogen-borrowing' (HB) amination has been expanded to secondary alcohols, which had previously been reported to react only in the presence of large amounts of co-catalysts. A range of cyclic and acyclic secondary alcohols were reacted with aromatic and aliphatic amines giving fair to excellent yields of the substitution products. The catalyst was also able to promote the cyclization of diols bearing a secondary alcohol group with primary amines to generate saturated N-heterocycles.

Fe-Catalyzed enaminone synthesis from ketones and amines

We have developed an iron-catalyzed direct olefination for enaminone synthesis, with saturated ketones as a source of olefins. This direct ketone β-functionalization reaction has readily available starting materials and a wide range of substrates and requires mild reaction conditions.

Silver(i)/base-promoted propargyl alcohol-controlled regio- or stereoselective synthesis of furan-3-carboxamides and (Z)-enaminones

A novel and facile regioselective synthesis of furan-3-carboxamides by a silver(i)/base-promoted reaction of propargyl alcohol with 3-oxo amides has been demonstrated. This one-pot protocol provides a rapid synthetic approach to diverse trisubstituted furan-3-carboxamides via cascade nucleophilic addition, intramolecular cyclization, elimination, and isomerization reactions. Employing a substituted propargyl alcohol, (Z)-enaminones have been obtained with high stereoselectivities by a Ag2CO3-promoted reaction starting from 3-oxo amides via C-N bond cleavage.

Water-promoted synthesis of enaminones: Mechanism investigation and application in multicomponent reactions

Highly stereoselective synthesis of Z-enaminones bearing reactive secondary amino group has been successfully performed in water using tertiary amino group functionalized enaminones under ambient conditions. An interesting promotion effect of water on the

KHSO4 assisted Michael addition-elimination reactions of formylated acetophenones in water: A facile general green synthetic route to 3-(alkyl/aralkyl/aryl)amino-1-arylprop-2-en-1-ones

A facile general green synthetic route to 3-(alkyl/aralkyl/aryl)amino-1- arylprop-2-en-1-ones in excellent yields has been developed by reacting formylated acetophenones with primary amines assisted by KHSO4 in water.

Acid-catalyzed cascade reactions of enaminones with aldehydes: C-H functionalization to afford 1, 4-dihydropyridines

An efficient acid-catalyzed approach to the synthesis of functional 1,4-dihydropyridines from the reaction of readily available enaminones with aldehydes has been developed. This methodology was realized by a cascade reaction involving first formation of divinylmethanes and subsequent intramolecular cyclization.