25209-66-9

Basic information

• Product Name: N-N-bis(2-hydroxyethyl)formamide
• Synonyms: N-N-bis(2-hydroxyethyl)formamide;Einecs 246-734-7;Formamide, N,N-bis(2-hydroxyethyl)-;N,N-Bis(beta-hydroxyethyl)formamide;N,N-Di(2-hydroxyethyl)formamide;N,N-Di-(beta-hydroxyethyl) formamide;Nsc 79862
• CAS NO: 25209-66-9
• Molecular Formula: C₅H₁₁NO₃
• Molecular Weight: 133.14574
• EINECS: 246-734-7
• Mol File: 25209-66-9.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 379 °C at 760 mmHg
• Flash Point: 183 °C
• Appearance: /
• Density: 1.203 g/cm³
• Vapor Pressure: 2.68E-07mmHg at 25°C
• Refractive Index: 1.493
• PKA: 14.06±0.10(Predicted)
• CAS DataBase Reference: N-N-bis(2-hydroxyethyl)formamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-N-bis(2-hydroxyethyl)formamide(25209-66-9)
• EPA Substance Registry System: N-N-bis(2-hydroxyethyl)formamide(25209-66-9)

Safety Data

• Hazardous Substances Data: 25209-66-9(Hazardous Substances Data)

Usage

General Description

N-N-bis(2-hydroxyethyl)formamide, also known as Diethanolisopropanolamine (DEIPA), is a chemical compound commonly used as an additive in cement grinding aids and concrete admixtures. It acts as a surfactant and has been found to improve the efficiency of cement grinding, reduce energy consumption, and enhance the strength and workability of concrete. DEIPA is a colorless liquid with a slightly ammoniacal odor, and it is considered to be non-toxic when used in appropriate concentrations. However, prolonged or direct exposure to high concentrations of DEIPA may cause irritation to the skin, eyes, and respiratory system. Therefore, proper handling and safety precautions should be followed when using this chemical in industrial applications.

InChI:InChI=1/C5H11NO3/c7-3-1-6(5-9)2-4-8/h5,7-8H,1-4H2

Upstream product

• 102-71-6 triethanolamine 
• 124-38-9 carbon dioxide 
• 111-42-2 2,2'-iminobis[ethanol] 
• 109-94-4 formic acid ethyl ester 
• 107-31-3 Methyl formate 
• 64-18-6 formic acid 
• 68-12-2 N,N-dimethyl-formamide 
• 201230-82-2 carbon monoxide 

Downstream Products

• 36024-66-5 N,N-Bis-(2-chlor-aethyl)-formamid 

Relevant articles and documents

Preparation and properties of starch-based film using N,N-bis(2-hydroxyethyl)formamide as a new plasticizer

N,N-Bis(2-hydroxyethyl)formamide (BHF) was synthesized efficiently and used as a new plasticizer for corn starch to prepare flexible starch film. The hydrogen bond interaction between BHF and starch was proven by Fourier-transform infrared (FT-IR) spectroscopy. By scanning electron microscope (SEM), starch granules were completely disrupted and a continuous phase was obtained. The crystallinity of corn starch and BHF-plasticized starch film (BSF) was characterized by X-ray diffraction (XRD). The water resistance of BSF was better than that of glycerol-plasticized starch film (GSF). Water vapor permeability of BSF was lower than that of GSF. Tensile strengths of BSF were inferior to those of GSF, while the elongations at break of BSF were higher than those of GSF.

Highly Efficient and Selective N-Formylation of Amines with CO2 and H2 Catalyzed by Porous Organometallic Polymers

The valorization of carbon dioxide (CO2) to fine chemicals is one of the most promising approaches for CO2 capture and utilization. Herein we demonstrated a series of porous organometallic polymers could be employed as highly efficient and recyclable catalysts for this purpose. Synergetic effects of specific surface area, iridium content, and CO2 adsorption capability are crucial to achieve excellent selectivity and yields towards N-formylation of diverse amines with CO2 and H2 under mild reaction conditions even at 20 ppm catalyst loading. Density functional theory calculations revealed not only a redox-neutral catalytic pathway but also a new plausible mechanism with the incorporation of the key intermediate formic acid via a proton-relay process. Remarkably, a record turnover number (TON=1.58×106) was achieved in the synthesis of N,N-dimethylformamide (DMF), and the solid catalysts can be reused up to 12 runs, highlighting their practical potential in industry.

Method for preparing formamide compound by catalyzing carbon dioxide hydrogenation with porous material

The invention belongs to the technical field of organic synthesis and heterogeneous catalysis, and particularly relates to a method for preparing a formamide compound by catalyzing carbon dioxide hydrogenation through a porous material. The method comprises the following steps: by taking a porous organic metal polymer as a catalyst, reacting an amine compound with carbon dioxide and hydrogen in anair atmosphere to prepare the formamide compound. The method has the advantages of high reaction efficiency, good selectivity, mild conditions, economy, environmental protection, simple operation andthe like; wherein a solid metal polymer material with large specific surface area, strong carbon dioxide adsorption, hierarchical pore channel distribution and highly dispersed metal centers is designed and synthesized as a reaction catalyst by changing a cross-linked copolymer proportion; the catalyst is especially used for catalytic synthesis of fine chemical N, N-dimethylformamide (DMF), doesnot need any additional solvent, alkali or other additives, and is convenient for separation and purification of DMF. The catalyst can be recycled; no special equipment is needed in the reaction, thereaction operation is simple, and further industrial application is facilitated.