25216-72-2

Usage

Uses

Used in Pharmaceutical Synthesis:
[2-(3-Bromo-phenyl)-ethyl]-carbamic acid methyl ester is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique structure, which includes a phenyl and bromo group, allows for the creation of molecules with specific receptor-targeting properties, potentially leading to the development of more effective drugs.
Used in Organic Chemistry:
In the field of organic chemistry, [2-(3-Bromo-phenyl)-ethyl]-carbamic acid methyl ester serves as a key building block for the synthesis of a wide range of organic molecules. Its versatility in reactions and the presence of functional groups make it a valuable component in the creation of complex organic structures.
Used in Medicinal Chemistry Research:
[2-(3-BroMo-phenyl)-ethyl]-carbaMic acid Methyl ester is also used as a research tool in medicinal chemistry, where it can help scientists understand the interactions between molecules and biological targets. Further research and testing may be necessary to fully comprehend its potential applications and optimize its use in drug development.

Upstream product

• 67-56-1 methanol 
• 72755-05-6 3-bromobenzoyl azide 
• 79-22-1 methyl chloroformate 
• 591-19-5 m-Bromoaniline 
• 6294-89-9 hydrazinecarboxylic acid methyl ester 
• 1202047-34-4 3-(3-bromophenyl)-1,1-diisopropylurea 
• 33322-41-7 3-bromo-benzoic acid bromoamide 
• 124-41-4 sodium methylate 

Downstream Products

• 24626-58-2 3-bromo-2,4,6-trinitro-aniline 
• 7072-80-2 5-methoxy-2,4-dinitroaniline 
• 116529-44-3 5-bromo-2,4-dinitro-aniline 
• 874299-09-9 1-(tert-butyl)-3-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea 
• 20940-44-7 N-(3-bromo-phenyl)-N'-methyl-urea 

Relevant academic research and scientific papers

Copper-Catalyzed Coupling of Amines with Carbazates: An Approach to Carbamates

A new approach for the preparation of carbamatesviathe copper-catalyzed cross-coupling reaction of amines with alkoxycarbonyl radicals generated from carbazates is described. This environmentally friendly protocol takes place under mild conditions and is compatible with a wide range of amines, including aromatic/aliphatic and primary/secondary substrates.

COUMARIN-LIKE CYCLIC COMPOUND AS MEK INHIBITOR AND USE THEREOF

Disclosed are a class of coumarin-like cyclic compounds as MEK inhibitors and pharmaceutical compositions comprising the compounds, and the use of same in the preparation of a drug for treating MEK-related diseases. Particularly disclosed are compounds as shown in formula (I) and pharmaceutically acceptable salts thereof or tautomers thereof.

Factor XIa Inhibitors

The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes.

Aniline carbamates: A versatile and removable motif for palladium-catalyzed directed c-h activation

The aniline carbamate is introduced as a new removable directing group for C-H activation. Its versatility and ability as a directing group are demonstrated by its use in the ortho-arylation of a wide variety of aniline derivatives under palladium(II) catalysis, with symmetric diaryliodonium salts as aryl donors. The reaction differs from previously reported arylations in its selectivity and its mechanism, as elucidated by kinetic and isotopic experiments. The directing group can also be easily removed under a variety of conditions.

Hindered ureas as masked isocyanates: Facile carbamoylation of nucleophiles under neutral conditions

Bigger is better: Sterically hindered dialkyl ureas undergo nucleophilic substitution at dramatically faster rates than their less hindered counterparts (see scheme). Steric decompression upon the formation of an intermediate isocyanate can explain this c