252193-58-1 Usage
Molecular weight
233.73 g/mol The mass of one mole of the chemical.
Appearance
Colorless to pale yellow liquid The chemical's physical state and color.
Boiling point
335.15°C The temperature at which the chemical changes from a liquid to a gas.
Melting point
Not applicable The chemical does not have a solid state.
Solubility
Slightly soluble in water, soluble in organic solvents The chemical's ability to dissolve in different solvents.
Functional groups
One ketone group (C=O) and one amino group (NH2) The specific chemical groups present in the molecule.
Reactivity
Reacts with strong acids, bases, and reducing agents The chemical's potential to undergo reactions with other substances.
Uses
Building block for the synthesis of organic compounds and drugs, reagent in chemical reactions, solvent in various applications The main applications of the chemical in the pharmaceutical industry and research.
Safety concerns
Potential health and environmental risks if not managed properly The need for proper handling and use of the chemical to avoid negative effects.
Check Digit Verification of cas no
The CAS Registry Mumber 252193-58-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,2,1,9 and 3 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 252193-58:
(8*2)+(7*5)+(6*2)+(5*1)+(4*9)+(3*3)+(2*5)+(1*8)=131
131 % 10 = 1
So 252193-58-1 is a valid CAS Registry Number.
252193-58-1Relevant articles and documents
MONOAM1NE REUPTAKE INHIBITORS
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Page/Page column 67, (2010/11/04)
The invention provides bupropion analogue compounds capable of inhibiting the reuptake of one or more monoamines. The compounds may selectively bind to one or more monoamine transporters, including those for dopamine, norepinephrine,and serotonin. Such compounds may be used to treat conditions that are responsive to inhibition of the reuptake of monoamines, including addiction, depression, and obesity
Diminished reactivity of ortho-substituted phenacyl bromides toward nucleophilic displacement
Kalendra, Diane M.,Sickles, Barry R.
, p. 1594 - 1596 (2007/10/03)
A systematic increase of substitution rates by tert-butylamine on α-bromopropiophenones is observed with meta or para substituents with increasing electron-withdrawing ability (k x 103 L M-1 min-1 = 12.7 (p-CH3), 15.7 (o-F), 20.5 (H), 20.0 (p-Cl), 23.6 (m-Cl), 27.3 (p-CF3)). Within an ortho-substituted series, the reactivities decrease (k x 103 L M-1 min-1 = 7.64 (o-OCH3), 5.31 (o-CH3), 2.85 (o-Cl), 2.40 (o-CF3)). Ortho-substitution results occur from rotational barrier effects and an Aδσ + Bδσ + repulsion. The major bonding contribution between reaction and α-substituent centers (A-B) is only the σ bond. When π bonding is allowed between A and B (meta/para-substitution), delocalization and stabilization of the reacting center occurs.
