253143-32-7

Upstream product

• 90719-32-7 (S)-4-Benzyl-2-oxazolidinone 
• 428874-41-3 (S)-5-[(tert-butyldiphenylsilyl)oxy]-4-ethylpentanoic acid 
• 253143-31-6 4-(tert-butyl-diphenyl-silanyloxymethyl)-hexan-1-ol 
• 428874-25-3 tert-butyl-(2-ethyl-pent-4-enyloxy)-diphenyl-silane 
• 253143-30-5 (R)-4-benzyl-3-((S)-2-ethylpent-4-enoyl)oxazolidin-2-one 
• 121074-21-3 (2S)-2-ethyl-4-penten-1-ol 

Downstream Products

• 253143-33-8 (2S,4S)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-2-methyl-hexanal 
• 428874-29-7 (2S,4S)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-2-methyl-hexan-1-ol 
• 382138-99-0 (2S,3S,4S,5S,6R,9S,11S)-9-Ethyl-2-((2S,3S)-2-hydroxy-3-methyl-hept-6-ynyl)-4-(4-methoxy-benzyloxy)-3,5,11-trimethyl-1-oxa-7-aza-spiro[5.5]undecan-8-one 
• 382138-88-7 (2S,4R,5S,6S,8S)-8-(tert-Butyl-diphenyl-silanyloxymethyl)-5-hydroxy-1-(4-methoxy-benzyloxy)-2,4,6-trimethyl-decan-3-one 
• 382138-95-6 (2S,4S,5S,6R,7R,8S)-8-[(4S,6S)-2,2-Dimethyl-6-((S)-1-methyl-pent-4-ynyl)-[1,3]dioxan-4-yl]-2-ethyl-7-(4-methoxy-benzyloxy)-4,6-dimethyl-nonane-1,5-diol 
• 382139-12-0 (2R,3S,4S,6S)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-2-[(2S,4S,5S)-2-(4-methoxy-phenyl)-5-methyl-[1,3]dioxan-4-yl]-4-methyl-octan-3-ol 
• 382138-89-8 (2S,3S,4R,5S,6S,8S)-8-(tert-Butyl-diphenyl-silanyloxymethyl)-1-(4-methoxy-benzyloxy)-2,4,6-trimethyl-decane-3,5-diol 
• 382139-19-7 (2S,4S,6S,7S,8S)-8-[(4S,6S)-2,2-Dimethyl-6-((S)-1-methyl-pent-4-ynyl)-[1,3]dioxan-4-yl]-2-ethyl-7-(4-methoxy-benzyloxy)-4,6-dimethyl-5-oxo-nonanoic acid amide 
• 382138-98-9 (2S,4S,5S,6R,7R,8S)-8-[(4S,6S)-2,2-Dimethyl-6-((S)-1-methyl-pent-4-ynyl)-[1,3]dioxan-4-yl]-2-ethyl-5-hydroxy-7-(4-methoxy-benzyloxy)-4,6-dimethyl-nonanoic acid amide 
• 382139-16-4 2,2-Dimethyl-propionic acid (2S,4S,5S,6R,7R,8S)-8-[(4S,6S)-2,2-dimethyl-6-((S)-1-methyl-pent-4-ynyl)-[1,3]dioxan-4-yl]-2-ethyl-5-hydroxy-7-(4-methoxy-benzyloxy)-4,6-dimethyl-nonyl ester 
• 382138-91-2 (2R,3R,4S,5S,6S,8S)-8-(tert-Butyl-diphenyl-silanyloxymethyl)-3-(4-methoxy-benzyloxy)-2,4,6-trimethyl-5-triethylsilanyloxy-decanal 
• 382138-96-7 (2S,4S,5S,6S,7S,8S)-8-[(4S,6S)-2,2-Dimethyl-6-((S)-1-methyl-pent-4-ynyl)-[1,3]dioxan-4-yl]-2-ethyl-7-(4-methoxy-benzyloxy)-4,6-dimethyl-5-triethylsilanyloxy-nonan-1-ol 
• 382138-90-1 (2S,4S,5S)-4-[(1S,2S,3S,5S)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-1,3-dimethyl-2-triethylsilanyloxy-heptyl]-2-(4-methoxy-phenyl)-5-methyl-[1,3]dioxane 
• 382139-18-6 (2S,4S,5S,6S,7S,8S)-8-[(4S,6S)-2,2-Dimethyl-6-((S)-1-methyl-pent-4-ynyl)-[1,3]dioxan-4-yl]-2-ethyl-7-(4-methoxy-benzyloxy)-4,6-dimethyl-5-triethylsilanyloxy-nonanoic acid amide 

Relevant academic research and scientific papers

A convergent three-component total synthesis of the powerful immunosuppressant (-)-sanglifehrin A

The potent immunosuppressive agent (-)-sanglifehrin A (5), initially discovered in a soil sample from Malawi, has been synthesized in a highly conver soil gent and stereocontrolled manner. The enantioselective approach relies on initial construction of th

Synthesis of the tripeptide (C1-N12) and hydroxylated hexadecene (C26-C41) domains of sanglifehrin A and C

Fully enantio-controlled routes to two major segments of the newly discovered immunosuppressants sanglifehrin A and C are described.