25445-35-6

Upstream product

• 52577-09-0 3-(chloromethyl)-4-methoxybenzaldehyde 
• 100-97-0 hexamethylenetetramine 
• 25445-34-5 1-methoxy-2,4-bis(chloromethyl)benzene 
• 76646-42-9 3-(hydroxymethyl)-4-methoxybenzaldehyde 
• 7697-37-2 nitric acid 
• 854627-56-8 6,6'-dimethoxy-3,3'-(2-oxa-propanediyl)-di-benzaldehyde 
• 7664-93-9 sulfuric acid 
• 3328-70-9 5-formyl-2-hydroxybenzaldehyde 
• 74-88-4 methyl iodide 
• 6738-23-4 2,4-dimethylanisole 

Downstream Products

• 2206-43-1 4-methoxyisophthalic acid 

Relevant academic research and scientific papers

Selective Electrochemical Oxygenation of Alkylarenes to Carbonyls

An efficient electrochemical method for benzylic C(sp3)-H bond oxidation has been developed. A variety of methylarenes, methylheteroarenes, and benzylic (hetero)methylenes could be converted into the desired aryl aldehydes and aryl ketones in moderate to excellent yields in an undivided cell, using O2 as the oxygen source and lutidinium perchlorate as an electrolyte. On the basis of cyclic voltammetry studies, 18O labeling experiments, and radical trapping experiments, a possible single-electron transfer mechanism has been proposed for the electrooxidation reaction.

AMINOGUANIDINE HYDRAZONES AS RETROMER STABILIZERS USEFUL FOR TREATING NEUROLOGICAL DISEASES

The present invention relates to novel aminoguanidine hydrazone-derivatives of Formula (I) which are effective as retromer stabilizers and useful as neuroprotecting drugs. The invention also relates to pharmaceutical compositions comprising the compounds and their use in therapy and diagnostic.

A new photoactivatable near-infrared-emitting QCy7 fluorophore for single-molecule super-resolution microscopy

A new photoactivatable fluorophore based on a quinone-cyanine-7 (QCy7) scaffold was synthesized and spectroscopically characterized. The fluorophore exhibits fluorescence in the near-infrared spectral window and a large Stokes shift. Its application in super-resolution microscopy as an antibody bioconjugate is demonstrated.

Chemoselective oxidative C(CO)-C(methyl) bond cleavage of methyl ketones to aldehydes catalyzed by CuI with molecular oxygen

Aldehyde Termination: A novel copper-catalyzed transformation from methyl ketones into aldehydes has been accomplished. This method is applicable to a wide range of aromatic and aliphatic methyl ketones and chemoselectively produces aldehydes, accompanied by the release of hydrogen (H2) and carbon dioxide (CO2) as by-products. Copyright