2562-48-3

Basic information

• Product Name: L-Phenylalanine, N-acetyl-L-phenylalanyl-, methyl ester
• CAS NO: 2562-48-3
• Molecular Formula: C21H24N2O4
• Molecular Weight: 368.433
• Mol File: 2562-48-3.mol
• Article Data: 19

Chemical Properties

• CAS DataBase Reference: L-Phenylalanine, N-acetyl-L-phenylalanyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Phenylalanine, N-acetyl-L-phenylalanyl-, methyl ester(2562-48-3)
• EPA Substance Registry System: L-Phenylalanine, N-acetyl-L-phenylalanyl-, methyl ester(2562-48-3)

Safety Data

• Hazardous Substances Data: 2562-48-3(Hazardous Substances Data)

Upstream product

• 5469-44-3 2-methyl-4-benzyl-4H-oxazolin-5-one 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 
• 13649-97-3 (S)-4-benzyl-2-methyl-4H-oxazol-5-one 
• 15028-44-1 DL-phenylalanine methyl ester 
• 38879-46-8 (Z)-4-benzylidene-2-methyl-5(4H)-oxazolone 
• 109927-10-8 racemic Ac-Phe-ΔPhe-OMe 
• 82690-96-8 N-Acetyldehydrophenylalanylphenylalanine methyl ester 
• 13082-29-6 L-phenylalanyl-L-phenylalanine methyl ester 
• 507-09-5 tiolacetic acid 
• 78087-68-0 N-(α-acetylamino-cinnamoyl)-L-phenylalanine 
• 1161-13-3 N-Cbz-L-Phe 
• 63-91-2 L-phenylalanine 
• 2018-61-3 (S)-2-acetylamino-3-phenylpropanoic acid 

Downstream Products

• 828-01-3 phenyllactic acid 
• 3618-96-0 (S)-N-acetylphenylalanine 
• 10030-31-6 (S)-2-((S)-2-acetamido-3-phenylpropanamido)-3-phenylpropanoic acid 

Relevant articles and documents

Postsynthetic Modification of Phenylalanine Containing Peptides by C-H Functionalization

New methods for peptide modification are in high demand in drug discovery, chemical biology, and materials chemistry; methods that modify natural peptides are particularly attractive. A Pd-catalyzed, C-H functionalization protocol for the olefination of phenylalanine residues in peptides is reported, which is compatible with common amino acid protecting groups, and the scope of the styrene reaction partner is broad. Bidentate coordination of the peptide to the catalyst appears crucial for the success of the reaction.

A traceless approach to amide and peptide construction from thioacids and dithiocarbamate-terminal amines

A novel and traceless strategy has been devised that allows a coupling of thioacids and dithiocarbamate-terminal amines. This strategy had been assumed to be dependent on the attachment of a functional equivalent of a cysteine side chain in earlier native chemical ligation approaches. This approach enables the traceless removal of CS2 to directly generate the desired amide bond and is compatible with a range of unprotected side chains of amino acid. The ability to produce amide or peptides by a traceless removal of the auxiliary is a significant virtue of the method. Meanwhile, the application of this new peptide-bond-forming reaction to the synthesis of novel endomorphin (EM) derivatives with various binding potencies was realized.

METHOD FOR STORING QUATERNARY AMMONIUM SALT

A method of improving the stability of a quaternary ammonium salt and a method of efficiently preparing the quaternary ammonium salt having improved stability.