256389-69-2

Upstream product

• 100-39-0 benzyl bromide 
• 317817-87-1 (S)-3-(4-Methoxy-phenyl)-3-methyl-pyrrolidin-2-one 
• 959903-74-3 methyl (R)-(+)-3-hydroxy-2-(4-methoxyphenyl)-2-methylpropionate 
• 100-46-9 benzylamine 
• 790260-90-1 (R)-(+)-2-(methoxycarbonyl)-2-(4-methoxyphenyl)propionic acid 
• 317817-83-7 (S)-1-((S)-2-Hydroxy-1-phenyl-ethyl)-3-(4-methoxy-phenyl)-3-methyl-pyrrolidin-2-one 
• 751467-94-4 (S)-4-Benzylamino-2-(4-methoxy-phenyl)-2-methyl-butyric acid methyl ester 

Relevant academic research and scientific papers

An efficient route to chiral, non-racemic 3-alkyl-3-arylpyrrolidines. Improved stereoselectivity in alkylation of bicyclic lactams and the effect of leaving groups

Chiral 3-alkyl-3-arylpyrrolidines were prepared from the substituted bicyclic lactams. Stereoselectivity in the alkylation of bicyclic lactams was improved by using an alkyl triflate or tosylate as the electrophile. (C) 2000 Published by Elsevier Science Ltd.

An easy access to (S)-pyrrolidinones and -pyrrolidines from chiral benzylic malonates

From chiral benzylic malonic acid esters (R)-(+)-4, available with high enantiomeric excesses by enzymatic hydrolysis (PLE acetonic powder), enantiomerically enriched pyrrolidinones 1 and pyrrolidines 2 were prepared. This rapid and competitive method was