2568-89-0

Basic information

• Product Name: Formaldehyde diisopropyl acetal
• Synonyms: 2,2'-(Methylenebisoxy)bispropane;Diisopropoxymethane;Formaldehyde diisopropyl acetal
• CAS NO: 2568-89-0
• Molecular Formula: C₇H₁₆O₂
• Molecular Weight: 132.2
• Mol File: 2568-89-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 127.1°C at 760 mmHg
• Flash Point: 16°C
• Appearance: /
• Density: 0.839g/cm³
• Vapor Pressure: 13.7mmHg at 25°C
• Refractive Index: 1.396
• CAS DataBase Reference: Formaldehyde diisopropyl acetal(CAS DataBase Reference)
• NIST Chemistry Reference: Formaldehyde diisopropyl acetal(2568-89-0)
• EPA Substance Registry System: Formaldehyde diisopropyl acetal(2568-89-0)

Safety Data

• Hazardous Substances Data: 2568-89-0(Hazardous Substances Data)

Usage

General Description

Formaldehyde diisopropyl acetal is a chemical compound that is commonly used as a protective group in organic synthesis. It is formed by the reaction of formaldehyde with isopropyl alcohol, resulting in a clear, colorless liquid with a faint, fruity odor. Formaldehyde diisopropyl acetal is often used as a reagent in the synthesis of complex organic molecules, particularly in the production of pharmaceuticals and fragrances. It serves as a protecting group for aldehydes, preventing them from reacting during various chemical processes, and can be easily removed under mild conditions, making it a valuable tool in synthetic chemistry. Additionally, it is considered to be a safer alternative to formaldehyde due to its reduced volatility and lower toxicity.

InChI:InChI=1/C7H16O2/c1-6(2)8-5-9-7(3)4/h6-7H,5H2,1-4H3

Upstream product

• 124-38-9 carbon dioxide 
• 67-63-0 isopropyl alcohol 
• 109-99-9 tetrahydrofuran 
• 3587-58-4 isopropoxymethyl chloride 
• 109-87-5 Dimethoxymethane 
• 4285-59-0 1,1-diisopropoxy-ethane 

Downstream Products

• 91968-51-3 Isopropyloxymethyl-benzyl-aether 
• 91764-45-3 Isopropyloxymethyl-phenethyl-ether 
• 101746-67-2 bis(2-phenylethyloxy)methane 
• 65757-61-1 (1-isopropoxyethyl)benzene 
• 100-42-5 styrene 
• 92904-23-9 1-Phenethyl-methoxy-isopropylether 
• 17493-73-1 2',6'-dimethyl-N-(isopropoxymethyl)-2-chloroacetanilide 
• 67535-24-4 2-Chloro-N-(2,6-diethyl-phenyl)-N-isopropoxymethyl-acetamide 
• 644981-24-8 N-isobutyl-N-(isopropoxymethyl)acetamide 
• 74-98-6 propane 
• 625-55-8 isopropyl formate 
• 5575-49-5 diisopropoxydimethylsilane 

Relevant articles and documents

Tailor-made Molecular Cobalt Catalyst System for the Selective Transformation of Carbon Dioxide to Dialkoxymethane Ethers

Herein a non-precious transition-metal catalyst system for the selective synthesis of dialkoxymethane ethers from carbon dioxide and molecular hydrogen is presented. The development of a tailored catalyst system based on cobalt salts in combination with selected Triphos ligands and acidic co-catalysts enabled a synthetic pathway, avoiding the oxidation of methanol to attain the formaldehyde level of the central CH2 unit. This unprecedented productivity based on the molecular cobalt catalyst is the first example of a non-precious transition-metal system for this transformation utilizing renewable carbon dioxide sources.

SYNTHESIS OF UNSYMMETRICAL 1,1-DIALKOXYALKANES AND THEIR SULFUR-CONTAINING ANALOGS

Acyclic acetals and 1,1-di(alkylthio)alkanes enter into exchange reactions in the presence of aprotic acids and of the KU-2 cation-exchange resin with the formation of the unsymmetric acetals and 1-alkoxy-1-alkylthioalkanes.In reaction with ethylal di(ethylthio)methane forms 3,5,7-trioxanonane in addition to ethylthioethoxymethane. 2-Methyl-4-thia-2-hexene was found in the products from the reaction of 1,1-di(ethylthio)-2-methylpropane with methylal.