256950-61-5

Upstream product

• 100-59-4 phenylmagnesium chloride 
• 851000-71-0 3-hydroxy-3-phenyl-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 100-58-3 phenylmagnesium bromide 
• 101385-93-7 3-oxo-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 78888-18-3 N-tert-butoxycarbonylprop-2-en-1-amine 
• 3360-54-1 3-bromo-2-phenylprop-1-ene 
• 352354-29-1 tert-butyl N-(2-bromo-2-propen-1-yl)-N-(2-propen-1-yl)carbamate 
• 256950-51-3 allyl-(2-phenyl-allyl)-carbamic acid tert-butyl ester 

Downstream Products

• 147410-43-3 tert-butyl 3-phenylpyrrolidine-1-carboxylate 

Relevant academic research and scientific papers

SMALL MOLECULE AGONISTS OF NEUROTENSIN RECEPTOR 1

Provided herein are small molecule neurotensin receptor agonists, compositions comprising the compounds, and methods of using the compounds and compositions comprising the compounds.

A new synthesis of 3-substituted pyrrolidines using iron catalysed cross-coupling reactions and ring closing metathesis

A series of 3-substituted N-Boc protected pyrrolidines have been prepared via iron catalysed cross-coupling between Boc protected N-allyl-N-(2-bromoallyl)amine 3 and organomagnesium compounds followed by ring closing metathesis and subsequent hydrogenatio

Ring closing metathesis of phenyl-substituted dienes

A series of phenyl-substituted heterodienes 2a-f and 6 was prepared and subjected to ring closing metathesis (RCM) to give differently phenyl- substituted dihydropyrroles and dihydrofuran.