2589-81-3

Basic information

• Product Name: Methanone, (4-hydroxy-1,3-phenylene)bis[phenyl-
• Synonyms: Dibenzoyl-2,4-phenol;5-Benzoyl-2-hydroxybenzophenon;2,4-Dibenzoyl-phenol
• CAS NO: 2589-81-3
• Molecular Formula: C20H14O3
• Molecular Weight: 302.329
• Mol File: 2589-81-3.mol
• Article Data: 2

Chemical Properties

• Melting Point: 105–106°C
• CAS DataBase Reference: Methanone, (4-hydroxy-1,3-phenylene)bis[phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (4-hydroxy-1,3-phenylene)bis[phenyl-(2589-81-3)
• EPA Substance Registry System: Methanone, (4-hydroxy-1,3-phenylene)bis[phenyl-(2589-81-3)

Safety Data

• Hazardous Substances Data: 2589-81-3(Hazardous Substances Data)

Usage

Preparation

Preparation by Friedel–Crafts acylationof phenol with benzoyl chloride in the ? presence of aluminium chloride at 200° for 15 min (69%) of 4-hydroxybenzophenone with benzoyl chloride in the presence of aluminium ? chloride from 100° up to 150°.

Upstream product

• 117-99-7 2-Hydroxybenzophenone 
• 76782-18-8 2-(dimethylaminomethylene)-1-phenylbutane-1,3-dione 
• 98-88-4 benzoyl chloride 
• 108-95-2 phenol 
• 16513-74-9 <4-(Benzoyloxy)phenyl>phenylketon 

Downstream Products

• 1334247-40-3 (S)-(3-(amino(phenyl)methyl)-4-hydroxyphenyl)(phenyl)methanone 
• 1334335-08-8 (4-hydroxy-3-(imino(phenyl)methyl)phenyl)(phenyl)methanone 

Relevant articles and documents

Self-Condensation of Enaminodiones as a Method for Benzene Ring Construction: Synthesis of Diacyl-Substituted Phenols and Catechols

A novel transition metal-free approach for the construction of the benzene core has been developed through self-condensation of available enaminodiones. Functionalized acyl-substituted phenols and catechols were obtained in 29-97% yields with high chemoselectivity under mild conditions. This base-promoted formal [4+2] annulation proceeds via cyclohexanone formation and involves the cascade transformation based on double Michael addition and aromatization (retro-Claisen cleavage and amine elimination).