58497-26-0

Upstream product

• 57-88-5 cholesterol 
• 98-88-4 benzoyl chloride 
• 604-32-0 cholesteryl benzoate 
• 26048-47-5 5α,6β-dibromocholestan-3β-yl benzoate 
• 114530-77-7 24,25-epoxycholesterol benzoate 

Downstream Products

• 1227078-51-4 C₃₉H₅₈O₄ 
• 61425-44-3 C₃₄H₅₀O₃ 
• 61425-45-4 C₃₄H₅₀O₃ 
• 27460-28-2 (24R)-3β,24-dibenzoyloxycholest-5-ene 
• 27460-29-3 (24S)-cholest-5-ene-3β,24-diyl dibenzoate 
• 55573-92-7 24-hydroxycholesterol benzoate 

Relevant academic research and scientific papers

Preparation of oxysterols by c–h oxidation of dibromocholestane with ru(Bpga) catalyst

Seven mono-and dihydroxycholesterols were prepared by direct C–H oxidation of the cholestane skeleton with a recently developed Ru(Bpga) catalyst (Ru(Bpga) = [RuCl (bpga) (PPh3 )] Cl; bpga = 2-(bis(pyridin-2-ylmethyl)amino)-N-(2,6-dimethylphenyl)acetamide)). Due to the high selectivity of the Ru(Bpga) complex for tertiary C–H, the reaction afforded a mixture of 25-, 20-, 17-, and 14-oxygenated cholesterols that could be easily separated by high-performance liquid chromatography. These results suggest that late-stage C–H oxidation could be a viable strategy for preparing candidate metabolites of biologically important molecules.