2611-02-1

Basic information

• Product Name: cyclohexylmethyl cyclohexanecarboxylate
• Synonyms: cyclohexylmethyl cyclohexanecarboxylate;Cyclohexanecarboxylic acid cyclohexylmethyl ester;Cyclohexanemethanol cyclohexanecarboxylate
• CAS NO: 2611-02-1
• Molecular Formula: C₁₄H₂₄O₂
• Molecular Weight: 224.33916
• EINECS: 220-032-0
• Mol File: 2611-02-1.mol
• Article Data: 60

Chemical Properties

• Boiling Point: 288.7°Cat760mmHg
• Flash Point: 129.1°C
• Appearance: /
• Density: 0.99g/cm³
• Vapor Pressure: 0.0023mmHg at 25°C
• Refractive Index: 1.479
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: cyclohexylmethyl cyclohexanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: cyclohexylmethyl cyclohexanecarboxylate(2611-02-1)
• EPA Substance Registry System: cyclohexylmethyl cyclohexanecarboxylate(2611-02-1)

Safety Data

• Hazardous Substances Data: 2611-02-1(Hazardous Substances Data)

Usage

Uses

Cyclohexylmethyl Cyclohexanecarboxyla?te is used in the synthetic preparation of esters using iodine-mediated oxidative condensation of alcohols.

Synthesis Reference(s)

The Journal of Organic Chemistry, 52, p. 4319, 1987 DOI: 10.1021/jo00228a032Tetrahedron Letters, 28, p. 6229, 1987 DOI: 10.1016/S0040-4039(00)61854-3

InChI:InChI=1/C14H24O2/c15-14(13-9-5-2-6-10-13)16-11-12-7-3-1-4-8-12/h12-13H,1-11H2

Upstream product

• 123-38-6 propionaldehyde 
• 110-83-8 cyclohexene 
• 120-51-4 benzoic acid benzyl ester 
• 487-68-3 mesytaldehyde 
• 2043-61-0 cyclohexanecarbaldehyde 
• 17610-00-3 3,5-Di-tert-butylbenzaldehyde 
• 100-52-7 benzaldehyde 
• 123-11-5 4-methoxy-benzaldehyde 
• 630-19-3 pivalaldehyde 
• 98-89-5 Cyclohexanecarboxylic acid 
• 100-49-2 cyclohexylmethyl alcohol 
• 643-79-8 o-phthalic dicarboxaldehyde 
• 590-86-3 isovaleraldehyde 
• 872-53-7 cyclopentanealdehyde 

Downstream Products

• 22733-94-4 benzyl cyclohexanecarboxylate 
• 14135-40-1 cyclohexilmethyl benzoate 
• 3289-28-9 ethyl cyclohexanecarboxylate 

Relevant articles and documents

Metal complex catalysts and method for catalytically reducing carboxylic acids

The invention relates to a metal complex catalyst, which contains at least one of metal complexes with a chemical formula comprising a structural unit represented by a formula I. According to the invention, the center metal of the metal complex catalyst is iridium, and the metal complex catalyst is composed of pentamethylcyclopentadienyl, a bitetrahydropyrimidine ligand and proper coordination anions; the metal complex catalyst has activity on a carboxylic acid reduction reaction, and a carboxylic acid compound is reduced into an alcohol compound in the presence of hydrogen; and the method ismild in reaction condition, can be carried out at room temperature, and is good in catalytic performance and high in reduction product yield.

Pd-Catalyzed Dehydrogenative Oxidation of Alcohols to Functionalized Molecules

A dehydrogenative oxidation reaction of primary alcohols to aldehydes catalyzed by a simple Pd/Xantphos catalytic system was developed under an argon or nitrogen atmosphere without oxidizing agents or hydrogen acceptors. The reaction product could be easily changed: under aerobic conditions, esters were obtained in aprotic solvents, whereas the corresponding carboxylic acids were produced in aqueous media. These oxidizing processes were applicable to the efficient synthesis of useful nitrogen-containing heterocyclic compounds such as indole, quinazoline, and benzimidazole via intramolecular versions of this reaction from amino alcohols.

Oxidative esterification of primary alcohols at room temperature under aqueous medium

Oxidative esterification of aliphatic primary alcohols with bromide and bromate couple in aqueous acidic medium at room temperature is reported with a wide range of substrate scope for both aliphatic and cyclic alcohols and obtained excellent yields of products.