26120-88-7

Basic information

• Product Name: Benzenesulfonyl fluoride, 2,4-dichloro-
• CAS NO: 26120-88-7
• Molecular Formula: C6H3Cl2FO2S
• Molecular Weight: 229.059
• Mol File: 26120-88-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzenesulfonyl fluoride, 2,4-dichloro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonyl fluoride, 2,4-dichloro-(26120-88-7)
• EPA Substance Registry System: Benzenesulfonyl fluoride, 2,4-dichloro-(26120-88-7)

Safety Data

• Hazardous Substances Data: 26120-88-7(Hazardous Substances Data)

Upstream product

• 21872-70-8 2,4-dichlorobenzenediazonium tetrafluoroborate 
• 5446-18-4 2,4-dichlorophenyl hydrazine hydrochloride 

Downstream Products

• 13656-58-1 2,4-Difluor-benzolsulfonsaeure-phenylester 
• 13656-60-5 2,4-difluoro-1-benzenesulfonamide 
• 13918-92-8 2,4-difluorobenzene-1-sulfonyl chloride 
• 13656-59-2 2,4-difluoro-N-phenylbenzenesulfonamide 
• 3782-65-8 2,4-Difluorobenzene sulfonyl fluoride 
• 1435-44-5 1-chloro-2,4-difluorobenzene 

Relevant articles and documents

Visible-Light-Mediated Synthesis of Sulfonyl Fluorides from Arylazo Sulfones

Sulfonyl fluorides are useful motifs for a wide range of applications in organic synthesis including sulfur (VI) fluoride exchange-based “click chemistry.” Herein, a visible-light-mediated synthesis of sulfonyl fluorides from arylazo sulfones is described. In the present study, K2S2O5 and N-fluorobenzenesulfonimide (NFSI) were used as the sulfonyl source and fluorinating agent, respectively, for visible-light-mediated fluorosulfonylation of arylazo sulfones to prepare various sulfonyl fluorides in 60–85% yield. This protocol is a synthetic approach to provide useful sulfonyl fluoride structures at room temperature. (Figure presented.).

Method for preparing aryl sulfonyl fluoride by using aryl hydrazine hydrochloride as raw material

The invention relates to a method for preparing aryl sulfonyl fluoride by using aryl hydrazine hydrochloride as a raw material. According to the method, aryl sulfonyl fluoride is synthesized by taking the aryl hydrazine hydrochloride as a raw material and adding a sulfur dioxide source and a fluorination reagent under the conditions of copper salt catalysis and alkali promotion through a strategy of insertion and fluorination of free radical sulfur dioxide. Compared with the prior art, the aryl sulfonyl fluoride is synthesized under the oxidation condition, and the influence of air on the reaction is not obvious in an experiment; and the reaction synthesis method is simple, good in selectivity, excellent in yield, mild in reaction condition, short in reaction time and universal to various aryl hydrazine hydrochloride substrates, and the method provides a new thought for synthesis of aryl sulfonyl fluoride.