26162-40-3Relevant academic research and scientific papers
Metal catalysed reactions of β,β′-tricarbonyl derivatives with isocyanates
Veronese, Augusto C.,Durini, Elisa,Bertolasi, Valerio,Basato, Marino,Tubaro, Cristina
experimental part, p. 8313 - 8316 (2010/11/17)
The reactions of β,β′-tricarbonyl derivatives with isocyanates are catalysed by 2 mol % transition metal acetylacetonates (e.g., [Co(acac)2] and [Zn(acac)2]) at room temperature. 3-Oxo-1,5-pentanedioic acid dimethylester (1) reacts with RNCO (R=Et, CH 2CHCH2, CH2Ph, Ph, 4-Cl-Ph) to give 1:1 adducts involving the formation of a new C-C bond between the intercarbonylic methylene and the isocyanato group. Under similar conditions 2,4,6-heptanetrione (2) reacts with the same isocyanates to afford pyridinone and pyranone derivatives resulting from the cyclisation of unstable 1:1 and 1:2 adducts.
Cycloadditions in Syntheses. Part 28. 2-Azabicyclohexane-3,5-dione and its Derivatives: Synthesis and Transformation to Azetidin-2-ones
Katagiri, Nobuya,Sato, Masayuki,Yoneda, Naoki,Saikawa, Satoshi,Sakamoto, Toshiyuki,et al.
, p. 1289 - 1296 (2007/10/02)
2-Azabicyclohexane-3,5-dione has been synthesized via photopyridone formation from 4-(dimethyl-t-butylsiloxy)- or 4-alkoxy-2-pyridones followed by mild acid hydrolysis.The title compound and its derivatives react with a variety of nucleophiles (ROH
REACTION OF ETHYL β-ALKYLAMINOCROTONATES IN THE PRESENCE OF ORGANIC ACID
Yamato, Masatoshi,Sato, Koichi,Hashigaki, Kuniko,Ninomiya, Mayumi
, p. 1263 - 1268 (2007/10/02)
Condensation of ethyl β-alkylaminocrotonates, obtained from ethyl acetoacetate and amines, in the presence of 3-mercaptopropionic acid gave 1,6-naphthyridine-2,5-dione derivatives.The structures of these compounds were determined on the basis of several i
