26343-75-9

Basic information

• Product Name: (S)-N-ForMyl MethaMphetaMine
• Synonyms: (S)-N-ForMyl MethaMphetaMine;L-(-)-N-Methyl-N- (α-Methylphenethyl)forMaMide;N-Methyl-N-[(1S)-1-Methyl-2-phenylethyl]forMaMide;N-methyl-N-[(2S)-1-phenylpropan-2-yl]formamide
• CAS NO: 26343-75-9
• Molecular Formula: C11H15NO
• Molecular Weight: 177
• Product Categories: Aromatics;Chiral Reagents;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 26343-75-9.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 325.4±21.0 °C(Predicted)
• Appearance: /
• Density: 1.002±0.06 g/cm3(Predicted)
• PKA: -0.53±0.70(Predicted)
• CAS DataBase Reference: (S)-N-ForMyl MethaMphetaMine(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-N-ForMyl MethaMphetaMine(26343-75-9)
• EPA Substance Registry System: (S)-N-ForMyl MethaMphetaMine(26343-75-9)

Safety Data

• Hazardous Substances Data: 26343-75-9(Hazardous Substances Data)

Usage

Uses

An impurity of (S)-(-)-Methamphetamine (M258790). Controlled substance.

Upstream product

• 67844-53-5 N-formyl ephedrine 
• 1630-35-9 (1R,2S)-N-<(2-Hydroxy-2-phenyl)-1-methyl-ethyl>-N-methylformamid 
• 593-51-1 methylamine hydrochloride 
• 103-79-7 1-phenyl-acetone 
• 103-82-2 phenylacetic acid 
• 123-39-7 N-Methylformamide 
• 1668-82-2 (2S,4S)-3,4-dimethyl-5-phenyl-1,3-oxazolidine 
• 7632-10-2 methamphetamin 
• 64-18-6 formic acid 
• 102732-72-9 <5-(4-Methoxyphenyl)-2-furylmethyl>-methyl-(1-methyl-2-phenyl-ethyl)-amin 
• 102732-70-7 <5-(4-Chlorphenyl)-2-furylmethyl>-methyl-(1-methyl-2-phenyl-ethyl)-amin 
• 102732-71-8 -(5-phenyl-2-furylmethyl)-amin 
• 67-56-1 methanol 

Relevant articles and documents

Compositions and Methods for Treating Cocaine, Nicotine, and Methamphetamine Dependence

This invention provides a composition of matter comprising a plurality of cocaine-succinyl-BSA, wherein the average ratio of cocaine-succinyl moieties to BSA is at least 7.0. This invention also provides a composition of matter comprising a plurality of nicotine-5-succinyl-BSA, wherein the average ratio of nicotine-5-succinyl moieties to BSA is at least 7.0. This invention further provides a composition of matter comprising a plurality of methamphetamine-5-succinyl-BSA, wherein the average ratio of methamphetamine-5-succinyl moieties to BSA is at least 7.0. This invention still further provides related pharmaceutical compositions, therapeutic methods, prophylactic methods, synthetic methods, and articles of manufacture.

A PROCESS FOR THE PREPARATION OF R-(-)-N, α-DIMETHYLPHENETHYLAMINE (LEVMETAMFETAMINE) OR S-(+)-N, α-DIMETHYLPHENETHYLAMINE (METHAMPHETAMINE) FROM d-EPHEDRINE OR L-EPHEDRINE RESPECTIVELY

A process for synthesis of R-(-)-N, α -Dimethylphenethylamine (Levmetamfetamine, formula I), or S-(+)-N, α - Dimethyl phenethylamine (Methamphetamine, formula II ), from d-ephedrine of formula III or l-ephedrine formula IV, the process comprising the steps of (a) acylating the d- or l-ephedrine base of formula III or formula IV with an acylating agent to make a reaction mixture containing a N- acylated ephedrines of formula V or formula VI ; (b) deoxygenation of N-acylated ephedrines to make the compound of the formula VII or Formula VIII by using Raney Nickel catalyst ; and (c) acid hydrolysis of the above deoxygenated products to get the levmetamfetamine or methamphetamine.

Unusually facile palladium catalysed oxidation of imidazolidines and oxazolidines

An unusually facile palladium catalysed oxidation of imidazolidines is described, affording in good yield, the monoamide of the corresponding diamine or the corresponding imidazolines. Oxazolidines derived from ephedrine react similarly.