2644-64-6Relevant articles and documents
Okazaki et al.
, p. 28,30,32-34 (1976)
Preparation method of synthetic phospholipid DPPC (dipalmitoyl phosphatidylcholine)
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Paragraph 0027, (2017/01/17)
The invention provides a method for artificially synthesizing phospholipid DPPC (dipalmitoyl phosphatidylcholine).The target product, DPPC, is synthesized from glyceryl phosphoryl choline and palmitic acid through condensation reaction.The method is simple in step, mild in reaction and suitable for industrial production.The prepared DPPC can be used for various medicines such as injection, tablets and capsules as a pharmaceutical adjuvant.
A rapid condensation between lysophosphorylcholine and fatty acids with an easily separable amine base
Acharya, Hukum P.,Kobayashi, Yuichi
, p. 2015 - 2018 (2007/10/03)
With 2,6-Cl2C6H3COCl and 1-methylimidazole, the title condensation completed at room temperature within 12 hours, which is shorter time than that with the standard DCC/DMAP system. Use of easily separable 1-methylimidazole from the crude product by chromatography is an additional advantage of the present reagent system. Georg Thieme Verlag Stuttgart.