26815-64-5

Upstream product

• 105-39-5 chloroacetic acid ethyl ester 
• 94-09-7 p-aminoethylbenzoate 
• 105-36-2 ethyl bromoacetate 
• 64-17-5 ethanol 
• 23284-85-7 4-((2-ethoxy-2-oxoethyl)amino)benzoic acid 
• 86364-40-1 4-(carbamoylmethyl-amino)-benzoic acid 
• 5698-54-4 N-(p-carboxyphenyl)glycine 
• 623-73-4 diazoacetic acid ethyl ester 
• 150-13-0 4-amino-benzoic acid 
• 6275-82-7 4-((cyanomethyl)amino)benzoic acid 

Downstream Products

• 874523-81-6 4-(4-oxo-3-phenyl-2-thioxo-imidazolidin-1-yl)-benzoic acid ethyl ester 
• 5698-54-4 N-(p-carboxyphenyl)glycine 
• 170799-80-1 ethyl N-(4-ethoxycarbonylphenyl)-N-ethylaminoacetate 
• 59081-60-6 N-(4-ethoxycarbonylphenyl)aminoacetic acid 
• 1054608-47-7 (S)-2-(4-{[2-(2,4-Diamino-6,7-dihydro-5H-cyclopentapyrimidin-5-yl)-ethyl]-ethyl-amino}-benzoylamino)-pentanedioic acid diethyl ester 
• 1053636-20-6 (S)-2-(4-{[2-(2,4-Diamino-6,7-dihydro-5H-cyclopentapyrimidin-5-yl)-ethyl]-methyl-amino}-benzoylamino)-pentanedioic acid diethyl ester 
• 170799-53-8 diethyl N-<4-pyrimidin-5-yl)ethyl>amino>benzoyl>-L-glutamate 
• 170799-63-0 ethyl 4-pyrimidin-5-yl)ethyl>-N-ethylamino>benzoate 
• 170799-62-9 ethyl 4-pyrimidin-5-yl)ethyl>-N-methylamino>benzoate 
• 170799-57-2 4-pyrimidin-5-yl)ethyl>-N-ethylamino>benzoic acid 
• 170799-61-8 ethyl 4-pyrimidin-5-yl)ethyl>amino>benzoate 
• 170799-56-1 4-pyrimidin-5-yl)ethyl>-N-methylamino>benzoic acid 
• 170799-68-5 ethyl 4--N-ethylamino>benzoate 
• 1028257-06-8 4-{[2-(2-Cyano-3-oxo-cyclopentyl)-ethyl]-ethyl-amino}-benzoic acid ethyl ester 

Relevant academic research and scientific papers

Stable radical cation salt initiated N-H insertion and related proton-transfer-delay three-component reaction

The N-H insertion reaction forms the single addition product exclusively, and does not require slow addition of the diazo component. More importantly, we present the reaction of anilines with both diazoacetates and azodicarboxylates in the presence of catalytic amounts of triarylaminium salt giving the corresponding complex unsymmetrical aminals in high yields. This is the first example of stable radical cation salt promoted proton-transfer-delay three-component reaction.

Iron-catalyzed oxidative tandem reactions with TEMPO oxoammonium salts: Synthesis of dihydroquinazolines and quinolines

A straightforward iron-catalyzed divergent oxidative tandem synthesis of dihydroquinazolines and quinolines from N-alkylanilines using a TEMPO oxoammonium salt as a mild and nontoxic oxidant has been developed. Fe(OTf) 2 was the Lewis acid cata

Novel 6-5 fused ring heterocycle antifolates with potent antitumor activity: Bridge modifications and heterocyclic benzoyl isosters of 2,4-diamino-6,7-dihydro-5H-cyclopenta[d]pyrimidine antifolate

Structural modifications of an extremely potent inhibitor of dihydrofolate reductase (DHFR) activity and tumor cell growth, N-[4-[3-(2,4-diamino-6,7-dihydro-5H-cyclopenta[d]pyrimidin-5-yl)propyl ]benzoyl]-L-glutamic acid (1), have led to the synthesis of

Potential Antiatherosclerotic Agents. 4. benzoic Acid Analogues of Cetaben

The synthesis of a series of analogues in which the alkyl group of cetaben is substituted with various functional groups or replaced entirely by a functionalized alkanoyl moiety is described.Also reported are the syntheses of branched-chain (alkylamino)be