5698-54-4

Basic information

• Product Name: 4-[(carboxymethyl)amino]benzoic acid
• Synonyms: 4-[(carboxymethyl)amino]benzoic acid
• CAS NO: 5698-54-4
• Molecular Formula: C₉H₉NO₄
• Molecular Weight: 195.17206
• Mol File: 5698-54-4.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 494.9°Cat760mmHg
• Flash Point: 253.1°C
• Appearance: /
• Density: 1.472g/cm³
• Vapor Pressure: 1.3E-10mmHg at 25°C
• Refractive Index: 1.66
• CAS DataBase Reference: 4-[(carboxymethyl)amino]benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(carboxymethyl)amino]benzoic acid(5698-54-4)
• EPA Substance Registry System: 4-[(carboxymethyl)amino]benzoic acid(5698-54-4)

Safety Data

• Hazardous Substances Data: 5698-54-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H9NO4/c11-8(12)5-10-7-3-1-6(2-4-7)9(13)14/h1-4,10H,5H2,(H,11,12)(H,13,14)

Upstream product

• 86364-40-1 4-(carbamoylmethyl-amino)-benzoic acid 
• 3926-62-3 sodium monochloroacetic acid 
• 150-13-0 4-amino-benzoic acid 
• 59748-90-2 4-Bromo-2-chloro-benzoic Acid 
• 56-40-6 glycine 
• 94-09-7 p-aminoethylbenzoate 
• 7732-18-5 water 
• 79-11-8 chloroacetic acid 
• 26815-64-5 ethyl 4-benzoate 
• 79-08-3 bromoacetic acid 
• 6275-82-7 4-((cyanomethyl)amino)benzoic acid 
• 39126-22-2 4-((1,3-diethoxy-1,3-dioxopropan-2-yl)amino)benzoic acid 
• 59081-60-6 N-(4-ethoxycarbonylphenyl)aminoacetic acid 

Downstream Products

• 26815-64-5 ethyl 4-benzoate 
• 1620220-63-4 3-(4-carboxyphenyl)-4-chloro-1,2,3λ⁵-oxadiazol-3-ylium-5-olate 
• 1620220-62-3 4-bromo-3-(4-carboxyphenyl)-1,2,3λ⁵-oxadiazol-3-ylium-5-olate 
• 7614-53-1 3-(4-carboxyphenyl)-1,2,3λ⁵-oxadiazol-3-ylium-5-olate 
• 111831-83-5 4-((carboxymethyl)(nitroso)amino)benzoic acid 
• 23284-85-7 4-((2-ethoxy-2-oxoethyl)amino)benzoic acid 

Relevant articles and documents

4-Halogeno-sydnones for fast strain promoted cycloaddition with bicyclo-[6.1.0]-nonyne

New sydnone derivatives have been synthesized and screened for their capacity to undergo fast copper-free cycloaddition reaction with bicyclo-[6.1.0]-nonyne. The influences of substitution in positions N-3 and C-4 of sydnones have been particularly studied leading to the identification of highly reactive partners for bio-orthogonal ligation reactions.

Discovery of chemoselective and biocompatible reactions using a high-throughput immunoassay screening

An immunoassay-based method was used to screen numerous combinations of dipoles and dipolarophiles for their ability to undergo chemoselective and biocompatible [3+2] cycloaddition reactions. The approach fulfills most of the requirements of the click concept and led to the discovery of a copper-catalyzed reaction that generates pyrazoles from sydnone and alkyne reagents. Copyright

Synthesis and evaluation of phenyl substituted sydnones as potential DPPH-radical scavengers

A series of phenyl substituted sydnones has been synthesized and their radical-scavenging activity has been studied on DPPH free radical. Out of eighteen compounds screened, nine compounds show interesting activity. A mechanism is presented whereby sydnones scavenge DPPH radical through donating H-atom at 4th-position. Its strong radical-scavenging activity mainly arises from 1, 2, 3-oxadiazolium-5-olate ring. Different substituents and their positions on the phenyl ring differently influence DPPH scavenging activity and therefore, may provide clues to design and develop better free-radical scavenging sydnones with multiple activities.