26928-23-4Relevant academic research and scientific papers
Stereodivergent hydrodefluorination of: Gem -difluoroalkenes: Selective synthesis of (Z)- and (E)-monofluoroalkenes
Kojima, Ryoto,Kubota, Koji,Ito, Hajime
supporting information, p. 10688 - 10691 (2017/10/06)
We have developed a novel approach for the stereodivergent hydrodefluorination of gem-difluoroalkenes using copper(i) catalysts to obtain stereodefined monofluoroalkenes. Both (Z)- and (E)-terminal monofluoroalkenes were obtained by the hydrodefluorination of gem-difluoroalkenes in the presence of copper(i) catalysts and diboron or hydrosilane, respectively, with high stereoselectivity. DFT calculations were conducted to elucidate the stereoselectivity.
Palladium-Catalyzed Stereoconvergent Formylation of (E/Z)-β-Bromo- β-fluorostyrenes: Straightforward Access to (Z)-α-Fluorocinnamic Aldehydes and (Z)-β-Fluorocinnamic Alcohols
Zemmouri, Rajae,Kajjout, Mohammed,Castanet, Yves,Eddarir, Said,Rolando, Christian
experimental part, p. 7691 - 7698 (2011/12/02)
We report here the stereoconvergent formylation of (E/Z)-β-bromo- β-fluorostyrene mixtures with carbon monoxide and sodium formate catalyzed by palladium. Optimization of reaction conditions leads to the corresponding pure (Z)-α-fluorocinnamaldehydes in g
Acceleration of alkenyltrimethylsilane fluorination under mild conditions using ultrasound
Ranjbar-Karimi, Reza
experimental part, p. 768 - 769 (2011/10/08)
Alkenyltrimethylsilanes are selectively fluorodesilated to alkenyl fluoride very readily by reaction with 1-chloromethyl-4-fluoro-1,4-diazoniabicyclo[2,2,2]octane bis-tetrafluoroborate (Selectfluor) and N-fluorobenzensulfonimids at room temperature under
Synthesis of monofluoroalkenes via Julia-Kocienski reaction
Prakash, G.K. Surya,Shakhmin, Anton,Zibinsky, Mikhail,Ledneczki, Istvan,Chacko, Sujith,Olah, George A.
experimental part, p. 1192 - 1197 (2011/02/22)
Monofluoromethyl 3,5-bis(trifluoromethyl)phenyl sulfone 1 was synthesized and employed in Julia-Kocienski fluoroolefination reaction with various ketones and aldehydes. Optimal reaction conditions were found to be the treatment of substrates with KOH or C
A Novel and Efficient Synthesis of Fluoromethyl Phenyl Sulphone and Its Use as a Fluoromethyl Wittig Equivalent
Inbasekaran, Muthiah,Peet, Norton P.,McCarthy James R.,LeTourneau, Michael E.
, p. 678 - 679 (2007/10/02)
A new synthesis of fluoromethyl phenyl sulphone (2) and the reaction of its conjugate base (3) with carbonyl compounds provides β-fluoro-alcohols (5), which are utilized to prepare terminal vinyl fluorides (8) via α-fluoro-α,β-unsaturated sulphones (6).
