26952-92-1Relevant articles and documents
Nucleophilic substitution of hydrogen–the Boger reaction sequence as an approach towards 8-(pyridin-2-yl)coumarins
Fatykhov, Ramil F.,Savchuk, Maria I.,Starnovskaya, Ekaterina S.,Bobkina, Maria V.,Kopchuk, Dmitry S.,Nosova, Emiliya V.,Zyryanov, Grigory V.,Khalymbadzha, Igor A.,Chupakhin, Oleg N.,Charushin, Valery N.,Kartsev, Viktor G.
, p. 299 - 300 (2019)
5,7-Dimethoxy-8-(3,6-diphenylpyridin-2-yl)coumarins were obtained from 5,7-dimethoxycoumarins and 3,6-diphenyl-1,2,4-triazines via the protocol comprising aromatic SNH substitution in the triazine ring followed by the Boger transform
Formation of coumarins by palladium(II)-catalyzed reaction of phenols with ethyl acrylates
Aoki, Shinya,Oyamada, Juzo,Kitamura, Tsugio
, p. 468 - 472 (2005)
The reaction of phenols with ethyl acrylates in the presence of a Pd(OAc)2 catalyst in trifluoroacetic acid did not yield dihydrocoumarins but gave coumarins, in contrast to the reaction of phenols with propiolates. The addition of K2S2O8 as an oxidant increased the yield of coumarins. The reaction of several phenols with ethyl cinnamate, ethyl crotonate, or ethyl acrylate gave the corresponding coumarin derivatives in moderate to good yields. The coumarin formation competed with the oxidative coupling of electron-rich phenols, which reduced the product yield.
Synthesis and NMR of 4-Aryl-3,4-dihydrocoumarins and 4-arylcoumarins
Sun, Jie,Wang, Yanfeng
, p. 7753 - 7758 (2015/02/02)
This paper described the synthesis and 1H and 13C NMR chemical shifts of a series of 4-aryl-3,4-dihydrocoumarin and 4-arylcoumarin derivatives based on a combination of 1H and 13C NMR, HSQC and HMBC experiments.
A convenient solid-phase synthesis of coumarins by TMSOTf-catalyzed intramolecular seleno-arylation of tethered alkenes
Tang,Li, Wen,Gao, Zhangyong
experimental part, p. 907 - 912 (2012/05/20)
TMSOTf-catalyzed intramolecular seleno-arylation of tethered alkenes was performed using polystyrene-supported succinimidyl selenide as the selenium source. This catalytic process provides an efficient method for the regioselective synthesis of dihydrocou