27096-64-6

Usage

InChI:InChI=1/C9H11NO/c1-2-7-11-9-6-4-3-5-8(9)10/h2-6H,1,7,10H2

Upstream product

• 55339-51-0 2-allyloxy-1-nitrobenzene 
• 88-75-5 2-hydroxynitrobenzene 
• 6622-73-7 4-acetamidophenyl allyl ether 
• 1746-13-0 allyl phenyl ether 
• 24892-63-5 1-allyloxy-2-iodobenzene 
• 186663-74-1 tert-butyl (2-hydroxyphenyl)carbamate 
• 106-95-6 allyl bromide 
• 95-55-6 2-amino-phenol 
• 1624-53-9 2-(benzylideneamino)phenol 
• 55000-07-2 o-(prop-2-enyloxy)phenyl azide 
• 614-80-2 2-(acetylamino)phenol 
• 91132-57-9 2-Acetylamino-phenyl-allyl-ether 

Downstream Products

• 77167-05-6 N-[2-(allyloxy)phenyl]-4-methylbenzenesulfonamide 
• 61364-10-1 chloro-(2-allyloxy-phenylhydrazono)-acetic acid ethyl ester 
• 55000-07-2 o-(prop-2-enyloxy)phenyl azide 
• 588700-28-1 N-[2-(3-methoxy-1-propynyl)-1-cyclopentenyl]-N'-[2-(2-propenyloxy)phenyl]urea 
• 91132-56-8 acetic acid-(5-allyl-2-hydroxy-anilide) 
• 857952-68-2 acetic acid-(2-hydroxy-5-propyl-anilide) 
• 113002-45-2 (E)-3-(2,3-dihydrobenzofuran-3-yl)-1-phenylpropene 
• 25125-40-0 1-(2-(allyloxy)phenyl)-2-(tetrafluoro-λ⁵-boraneyl)diazene 
• 1446029-14-6 [2-(allyloxy)phenyl](phenyl)selane 
• 1606177-24-5 1-(2,3-dihydrobenzofuran-3-yl)-N-morpholinomethanesulfonamide 
• 1620218-03-2 C₁₃H₁₈N₂O₄S 
• 1620218-02-1 1-((2-(allyloxy)phenyl)diazenyl)pyrrolidine 
• 98-54-4 para-tert-butylphenol 
• 4469-78-7 2-propoxyaniline 

Relevant academic research and scientific papers

Copper-catalyzed three-component reaction of arylhydrazine hydrochloride, DABSO, and NFSI for the synthesis of arenesulfonyl fluorides

This paper reports a convenient copper-catalyzed three-component conversion of arylhydrazine hydrochlorides to arenesulfonyl fluorides in good yields under mild conditions, using 1,4-diazabicyclo [2.2.2]octane bis(sulfur dioxide) (DABSO) as a sulfonyl source andN-fluorobenzenesulfonimide (NFSI) as a fluorine source based on a radical sulfur dioxide insertion and fluorination strategy. Notably, arylhydrazine hydrochloride is used as a safe precursor of aryl radicals.

An efficient approach to 3-thioether-functionalized 2,3-dihydrobenzofurans via a metal-free intramolecular radical cyclization/thiolation cascade reaction

A diverse series of 3-thioether-functionalized 2,3-dihydrobenzofurans were prepared by an intramolecular radical cyclization/thiolation cascade reaction of alkenyl-tethered arenediazonium salts with thiophenols under transition-metal-free conditions. The

Base-mediated intramolecular one-pot double-cyclization of epoxide-tethered 2-fluorobenzenesulfonamides: An avenue to 1,4-benzoxazine-fused benzothiaoxazepine-1,1-dioxides

Herein, we describe the synthesis of hitherto unknown 1,4-benzoxazine-fused benzothiaoxazepine-1,1-dioxides by a NaH-promoted intramolecular one-pot double-cyclization of epoxide-tethered 2-fluorobenzene sulfonamides. Mechanistically, the reactions proceed via an intramolecular epoxide ring-opening followed by an intramolecular nucleophilic aromatic substitution. The high yields, mild conditions, complete regio- and diastereoselectivity, and a wide substrate scope render this protocol well suited for drug discovery efforts.

Copper-free Sandmeyer-type Reaction for the Synthesis of Sulfonyl Fluorides

A copper-free Sandmeyer-type fluorosulfonylation reaction is reported. Utilizing Na2S2O5 and Selectfluor as the sulfur dioxide and fluorine sources, respectively, aryldiazonium salts were transformed into sulfonyl fluorides. The one-pot direct synthesis of sulfonyl fluorides from aromatic amines was also realized via in situ diazotization. The practicality of this method was demonstrated by the broad functional group tolerance, gram-scale synthesis, and late-stage fluorosulfonylation of natural products and pharmaceuticals.

Intramolecular Aminoazidation of Unactivated Terminal Alkenes by Palladium-Catalyzed Reactions with Hydrogen Peroxide as the Oxidant

The palladium-catalyzed aminoazidation of aminoalkenes yielding azidomethyl-substituted nitrogen-containing heterocycles was developed. The procedure requires oxidative conditions and occurs at room temperature in the presence of hydrogen peroxide and NaN3 as the azide source. These conditions provide selective exo-cyclization/azidation of the carbon-carbon double bond, furnishing a versatile approach toward five-, six-, and seven-membered heterocyclic rings.

Process for synthesizing ramalin not using Tin as a heavy metal

The present invention relates to a method for synthesizing ramalin. More particularly, the present invention relates to the method for preparing ramalin by conducting a reaction of a glutamic acid derivative manufactured by using alkyl chloroformate with

Pd-Catalyzed Enantioselective Double Heck Reaction

An asymmetric Pd-catalyzed intramolecular followed by an intermolecular double Heck reaction of arenediazonium salts with simple alkenes is disclosed. This reaction features mild reaction conditions, simple operation, and excellent functional group tolera

Copper(ii)-catalyzed c-n coupling of aryl halides and n-nucleophiles promoted by quebrachitol or diethylene glycol

Herein, we report the natural ligand quebrachitol (QCT) as a promoter for a Cu(II) catalyst, which is highly effective for N-Arylation of various amines and related aryl halides. A series of diarylamine derivatives were obtained in high yields by using diethylene glycol (DEG) as both ligand and solvent. The C-N coupling reactions proceed under mild conditions and exhibit good functional group tolerance.

Self-Assembled Magnetic Gold Catalysts from Dual-Functional Boron Clusters

A new class of core–shell magnetic gold nanocomposites is prepared in a raspberry-like fashion by the controlled supramolecular host–guest assembly of γ-cyclodextrins (γ-CDs) and boron clusters. In this work, Cs2[closo-B12H12], a fundamental boron cluster, can play a dual role in the preparation of highly monodispersed Au nanoparticles and in the immobilization of Au nanoparticles on the γ-CDs@Fe3O4 surface as an effective anchor. This facile and spontaneous supramolecular strategy allows for the control of the size and composition of the highly stable gold composites. Furthermore, the obtained AuNPs@Fe3O4 composites exhibit an excellent catalytic activity and recyclability for the selective reduction of nitroaromatics to their corresponding aniline compounds, and the fastest reaction can be achieved within 20 s with a high conversion and selectivity at room temperature, which is better than that obtained previously in studies on metal nanoparticle composites as catalysts.

Hexafluoro-2-propanol-assisted quick and chemoselective nitro reduction using iron powder as catalyst under mild conditions

Hexafluoro-2-propanol as the promoter for the quick nitro reduction using a combination of iron powder and 2 N HCl aqueous solution is reported. This methodology has several positive features, as it is of room temperature, remarkably short reaction time. A wide range of substrates including those bearing reducible functional groups such as aldehyde, ketone, acid, ester, amide, nitrile, halogens, even allyl, propargyl and heterocycles are chemoselectively reduced in good to excellent yields, even on gram scale. Notably, the highly selective reduction of 3-nitrophenylboronic acid is achieved quantitatively. The reduction is also tolerant of common protecting groups, and aliphatic nitro compound, 1-nitrooctane can be reduced successfully.