271-42-1

Basic information

• Product Name: 2H-Indazole
• Synonyms: 2H-Indazole
• CAS NO: 271-42-1
• Molecular Formula: C₇H₆N₂
• Molecular Weight: 118.13594
• Mol File: 271-42-1.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 134.7±13.0 °C(Predicted)
• Appearance: /
• Density: 1.242±0.06 g/cm3(Predicted)
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 14.00±0.30(Predicted)
• CAS DataBase Reference: 2H-Indazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Indazole(271-42-1)
• EPA Substance Registry System: 2H-Indazole(271-42-1)

Safety Data

• Hazardous Substances Data: 271-42-1(Hazardous Substances Data)

Upstream product

• 614-63-1 1,3-di-o-tolyltriazene 
• 612-24-8 o-nitrobenzonitrile 
• 95-53-4 o-toluidine 
• 584-70-3 N-benzoyl-2-methylaniline 
• 33334-11-1 2H-indazol-2-amine 
• 7409-30-5 p-nitrobenzylamine 
• 23300-97-2 2-tosyl-2H-indazole 
• 271-44-3 benzimidazole 
• 4498-67-3 1H-Indazole-3-carboxylic acid 
• 874-05-5 3-aminoindazole 
• 29110-74-5 3-chloroindazole 
• 65782-99-2 benzoic acid-(N-nitroso-o-toluidide) 
• 102309-00-2 2-hydrazino-cinnamic acid 
• 6967-12-0 6-amino-1H-indazole 

Downstream Products

• 1188513-95-2 1-(4-(2H-indazol-2-yl)phenyl)ethan-1-one 
• 1037827-19-2 N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-2-(2H-indazol-2-yl)nicotinamide 
• 1439359-45-1 2-(2H-indazol-2-yl)-1-phenylethanone 
• 1426937-52-1 C₂₂H₁₉ClN₂O 

Relevant articles and documents

Proton Transfer Tautomerism in the Excited State of Indazole in Acetic Acid: Tautomerization via Double Proton Switching

It is shown that the S1 state of 1H-indazole in acetic acid undergoes double proton transfer along the hydrogen bonds in the indazole-acetic acid complex.The proton transfer converts 1H-indazole into 2H-indazole.The rate of proton transfer is estimated to be 2.7x109 s1- from transient fluorescence measurements.

Consecutive condensation, C-N and N-N bond formations: A copper-catalyzed one-pot three-component synthesis of 2 H -indazole

2H-Indazoles are synthesized using copper-catalyzed, one-pot, three-component reactions of 2-bromobenzaldehydes, primary amines, and sodium azide. A copper catalyst plays the key role in the formation of C-N and N-N bonds. This method has a broad substrate scope with a high tolerance for a variety of functional groups.

2-substituted indazoles from electrogenerated ortho-nitrosobenzylamines

An electrochemical methodology for an efficient access to ortho- nitrosobenzylamines has been developed. These products cyclize intramolecularly producing the desired 2-substituted indazoles in high yields. The electrochemical procedure overcomes limitations of previous chemical methods.