27103-47-5Relevant articles and documents
Ε - propionic acid is oneself ester base - ε - caprolactone and its preparation method (by machine translation)
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Paragraph 0031-0033, (2017/09/26)
The invention discloses Epsilon-propionic-n-hexyl-Epsilon-caprolactone, having a structural formula shown as below. The invention further discloses a preparing method of the Epsilon-propionic-n-hexyl-Epsilon-caprolactone. The preparing method includes allowing an acidic compound and an alcoholic compound to esterify in organic solvent through an acid catalyst to obtain an n-hexyl acrylate compound, and allowing addition and Baeyer-Villiger oxidation of the n-hexyl acrylate compound and an alkene compound in the organic solvent through a basic catalyst and the acidic catalyst to obtain the Epsilon-propionic-n-hexyl-Epsilon-caprolactone compound. The Epsilon-propionic-n-hexyl-Epsilon-caprolactone is a novel Epsilon-lactone compound having characteristic fragrance of alcoholic sweet rice wine and belongs to latest research achievements on Epsilon-lactone compounds having characteristic fragrance at home and abroad.
Transesterification of acrylates by heterogeneous basic catalysis
Adriana, Maldonado,Nadine, Essayem,Lorraine, Christ,Fran?ois, Figueras
, p. 1 - 8 (2013/09/24)
Different solid basic catalysts including CsF/αAl2O 3, KF/αAl2O3, Ca(NO3) 2/γAl2O3, NaNO3/γAl 2O3, LiNO3/γAl2O3 were evaluated for the transesterification of ethyl acrylate by n-hexanol. All of them are active and selective in the transesterification reaction under mild conditions and without solvent, using a 1/1 molar ratio of reactants. Ca/γAl2O3 was shown to be the most selective of this set of catalysts and it could be recycled three times without lost of selectivity.
Nanostructure formation in aqueous solution of amphiphilic copolymers of 2-(N,N-dimethylaminoethyl)methacrylate and alkylacrylate: Characterization, antimicrobial activity, DNA binding, and cytotoxicity studies
Dutta, Pranabesh,Dey, Joykrishna,Shome, Anshupriya,Das, Prasanta Kumar
experimental part, p. 298 - 311 (2012/06/01)
Three amphiphilic random copolymers poly(2-(dimethylaminoethyl) methacrylate-co-alkylacrylate) (where, alkyl = hexyl, octyl, dodecyl) with 16 mol% hydrophobic substitution were synthesized. Surface tension, viscosity, fluorescence probe, dynamic light scattering (DLS), as well as transmission electron microscopic (TEM) techniques were utilized to investigate self-assembly formation by the hydrophobically modified polymers (HMPs) in pH 5. Formation of hydrophobic domains through inter-polymer chain interaction of the copolymer in dilute solution was confirmed by fluorescence probe studies. Average hydrodynamic diameter of the copolymer aggregates at different polymer concentration was measured by DLS studies. The copolymer with shorter hydrophobic chain exhibits larger hydrodynamic diameter in dilute solution, which decreased with either increase of concentration or increase of hydrophobic chain length. TEM images of the dilute solutions of the copolymers with shorter as well as with longer hydrophobic chain exhibit spherical aggregates of different sizes. The antimicrobial activity of the copolymers was evaluated by measuring the minimum inhibitory concentration value against one Gram-positive bacterium Bacillus subtilis and one Gram-negative bacterium Escherichia coli. The copolymer with the octyl group as pendent hydrophobic chain was found to be more effective in killing these microorganisms. The interaction of the cationic copolymers with calf-thymus DNA was studied by fluorescence quenching method. The polymer-DNA binding was found to be purely electrostatic in nature. The hydrophobes on the polymer backbone were found to have a significant influence on the binding process. Biocompatibility studies of the copolymers in terms of cytotoxicity measurements were finally performed at different concentrations of the HMPs to evaluate their potential application in biomedical fields.
