27130-46-7 Usage
Uses
Used in Chemical Synthesis:
O-Benzoyl-N-methylhydroxylamine Hydrochloride is used as a benzoylation reagent for the a-oxygenation of aldehydes and ketones. It aids in the formation of various chemical intermediates and final products by introducing a benzoyl group to the molecule.
Used in NHC-catalyzed Redox Esterification and Cycloaddition Reactions:
In this application, O-Benzoyl-N-methylhydroxylamine Hydrochloride acts as a key reactant, enabling the efficient conversion of starting materials into ester and cyclic products under the catalysis of N-heterocyclic carbenes (NHCs).
Used in Pd/pyrrolidine-catalyzed Tsuji-Trost Cyclization of Aldehydes:
O-Benzoyl-N-methylhydroxylamine Hydrochloride is utilized as a reactant in the palladium and pyrrolidine-catalyzed version of the Tsuji-Trost reaction, which is a powerful method for the cyclization of aldehydes to form complex molecular structures.
Used in the Synthesis of α-acyloxy Ketones via Oxyacylation Reaction:
O-Benzoyl-N-methylhydroxylamine Hydrochloride is employed in the preparation of α-acyloxy ketones through an oxyacylation reaction, which is an important synthetic strategy for constructing carbonyl-containing molecules with additional oxygen-containing functional groups.
Check Digit Verification of cas no
The CAS Registry Mumber 27130-46-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,1,3 and 0 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 27130-46:
(7*2)+(6*7)+(5*1)+(4*3)+(3*0)+(2*4)+(1*6)=87
87 % 10 = 7
So 27130-46-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H9NO2.ClH/c1-9-11-8(10)7-5-3-2-4-6-7;/h2-6,9H,1H3;1H
27130-46-7Relevant academic research and scientific papers
A general method for the α-acyloxylation of carbonyl compounds
Beshara, Cory S.,Hall, Adrian,Jenkins, Robert L.,Jones, Kerri L.,Jones, Teyrnon C.,Killeen, Niall M.,Taylor, Paul H.,Thomas, Stephen P.,Tomkinson, Nicholas C. O.
, p. 5729 - 5732 (2007/10/03)
(Chemical Equation Presented) A simple, one-pot method for the α-acyloxylation of carbonyl compounds that proceeds at room temperature in the presence of both moisture and air has been developed. Treatment of a variety of aldehydes and both cyclic and acy
Direct O-Acylation of Hydroxylamine and N-Monosubstituted Hydroxylamines by 1-Benzoylimidazole
Geffken, Detlef
, p. 744 - 746 (2007/10/02)
Under suitable conditions 1-benzoylimidazole (2) reacts with hydroxylamines 3 to give O-benzoylhydroxylamines 4, which are isolated as their hydrochlorides 5 in 55-83percent yields.
Synthesis and Decomposition of the N-Alkyl-N-nitro-O-benzoylhydroxylamines
White, Emil H.,Reefer, John,Erickson, Ronald H.,Dzadzic, Petar M.
, p. 4872 - 4876 (2007/10/02)
Nitration of N-alkyl-O-benzoylhydroxylamines yields the correspondng N-nitro derivatives.At modest temperatures these compounds decompose to yield alkyl benzoates, alkenes, benzoic acid, and nitrous oxide.In the case of primary alkylnitrohydroxylamines, nitroalkanes and alkyl nitrates are also formed.The alkyl benzoates are products of ionic reactions since skeletal rearrangements characteristics of carbonium ions occur.The insensivity of the rates of decomposition to solvent polarity suggests that the rate-determining step is a rearrangement rather than direct ionization.
