1030-23-5

Usage

Explanation

The compound consists of 17 carbon atoms, 16 hydrogen atoms, and 3 oxygen atoms.

Explanation

The physical form of the compound is a white, crystalline solid.

Explanation

The compound has a pleasant, sweet, and floral scent.

Explanation

Due to its pleasant scent, it is used to add flavor and fragrance to various food products and perfumes.

Explanation

The compound is used in the production of various pharmaceuticals, contributing to the development of new medications.

Explanation

1-oxo-1-phenylpropan-2-yl benzoate serves as an intermediate in organic synthesis, aiding in the creation of other chemical compounds.

Explanation

Studies have been conducted to explore the compound's potential to reduce inflammation, which could lead to new applications in the medical field.

Appearance

White, crystalline powder

Odor

Sweet, floral

Usage as a flavoring agent

Foods and perfumes

Usage in pharmaceuticals

Production of medications

Application in organic synthesis

Intermediate compound

Potential anti-inflammatory properties

Researched for its effects

Upstream product

• 4304-93-2 2-methyl-1-methoxy-1-phenyl-oxirane 
• 65-85-0 benzoic acid 
• 64-17-5 ethanol 
• 4773-35-7 1-chloro-1-phenylpropan-2-one 
• 582-25-2 Potassium benzoate 
• 2114-00-3 2-bromo-1-phenyl-1-propanone 
• 93-58-3 benzoic acid methyl ester 
• 1774-47-6 trimethylsulfoxonium iodide 
• 98-88-4 benzoyl chloride 
• 27130-46-7 N-methyl-O-(phenylcarbonyl)hydroxylamine hydrochloride 
• 93-55-0 1-phenyl-propan-1-one 
• 5650-40-8 2-hydroxypropiophenone 
• 28330-55-4 N-(tert-butyloxycarbonyl)-N-methyl-O-benzoyl-hydroxylamine 
• 75-07-0 acetaldehyde 

Downstream Products

• 88196-06-9 syn-1-phenylpropane-1,2-diol 
• 40421-52-1 (1RS,2SR)-1-phenylpropane-1,2-diol 
• 116782-33-3 Benzoic acid (1S,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl ester 
• 116782-33-3 Benzoic acid (1R,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl ester 

Relevant academic research and scientific papers

C–O bond formation via oxidative-coupling pathway in eutectic mixture of choline chloride/urea as a green solvent

C–O bond formation between terminal alkenes/benzyl alcohols as an arylcarboxy surrogate and carbonyl compounds in a biodegradable deep eutectic solvent (DES) based on choline chloride and urea was performed. By employment of TBAI as catalyst and TBHP as oxidant, various derivatives of carbonyl compounds were benzylated in α position in good to high yield at 90 °C. Moreover, α-oxybenzoylation of diethyl malonate with carboxylic acids was performed in the above-mentioned DES by employment of NaI as the catalyst and TBHP as the oxidant at 60 °C.

Methylsulfinyl (Dimsyl) anion as umpolung catalyst for the chemoselective cross-benzoin reaction of α-diketones with aldehydes

The hitherto unreported ability of the methylsulfinyl carbanion (dimsyl anion) to generate acyl anion equivalents is described. The dimsyl anion, in fact, efficiently catalyzes chemoselective intermolecular cross-benzoin condensations of diaryl α-diketones (benzils) with various aromatic and aliphatic aldehydes to give the corresponding aryl-aryl and aryl-alkyl benzoin benzoates in an atom-economic fashion. The dimsyl anion acts as an environmentally friendly alternative to the toxic cyanide anion and it is obtained by in situ deprotonation of dimethyl sulfoxide (DMSO) solvent with a catalytic amount of a strong base, potassium tert-butoxide (t-BuOK) the optimal promoter. The assumption that the methylsulfinyl carbanion is the active catalyst in the title transformation is supported by electrospray ionization mass spectrometry (ESI-MS) experiments. Copyright

Copper(I)-Catalyzed α-Acryloyloxylation of Ketones with α,β-Unsaturated Carboxylic Acids To Form α-Acryloyloxy Ketones

An efficient method for the α-C–H acryloyloxylation of ketones with α,β-unsaturated carboxylic acids was developed, using copper(I) as a catalyst. The most concise approach to form α-acryloyloxy ketones is through direct oxidative coupling at the α-C(sp3)–H position of ketones. This method gives the products in high yields, and has a wide substrate scope in terms of both ketones and unsaturated carboxylic acids. A copper(I)-catalyzed reaction mechanism is proposed based on the results of control experiments.

Unified and Benign Synthesis of Spirooxindoles via Bifunctional and Recyclable Iodide-Salt-Catalyzed Oxidative Coupling in Water

Herein we develop a novel micellar catalytic system based on amphiphilic bifunctional iodide salts for oxidative intramolecular α-oxygenation and α-amination of carbonyl substrates in water, thus enabling a unified and benign synthesis of various 2-oxindo

One-pot synthesis of acyloxy carbonyl compounds from ketones using a Pybox-copper(II) catalyst

We have described the first efficient one-pot method for the synthesis of acyloxy carbonyl compounds from ketones catalyzed by a Pybox-Cu(ii) complex under mild conditions. A series of α-acyloxy ketone products were obtained in good to excellent yields.

α-Acetoxyarone synthesis via iodine-catalyzed and tert-butyl hydroperoxide-mediateded self-intermolecular oxidative coupling of aryl ketones

We present a metal-free method for α-acetoxyarone synthesis by self-intermolecular oxidative coupling of aryl ketones using I2?tert-butyl hydroperoxide (TBHP). Under the optimum conditions, various aryl ketones gave the corresponding products i

Preparation method of alpha-acyloxy ketone compounds

The invention relates to a preparation method of alpha-acyloxy ketone compounds. The preparation method comprises the following steps: adding a ketone compound, a copper catalyst and an organosiliconreagent into an N,N-dialkylamide organic solvent, and reacting at 80 DEG C for 24 hours to obtain the alpha-acyloxy ketone. The ketone compound is used as a raw material, and by activating a C (spa keto-carbonyl group, an efficient, simple and convenient new method for constructing the C(sp)-O bond is successfully realized, and a series of alpha-acyloxy ketone compounds are obtained, so the reaction yield is good, the substrate application range is wide, the operation is simple and convenient, and the reaction has high atom and step economy.

Metal-free one-pot α-benzoxylation of benzylic alcohols with acids or aldehydes

A metal-free strategy has been developed for α-benzoxylation of benzylic alcohols with acids or aldehydes. The reaction proceeds via sequential oxidation and α-benzoxylation in one pot. Importantly, the reactions are performed in metal-free condition and utilize cheap aqueous TBHP as an oxidant, affording α-benzoxy ketones in moderate to good yields.

Copper-catalyzed α-C-H acyloxylation of carbonyl compounds with terminal alkynes

Herein, a copper/TBHP catalyst system for the α-C-H acyloxylation of carbonyl compounds is developed using terminal alkynes as the acyloxy source. A variety of carbonyl compounds and terminal alkynes are tolerated in this reaction. In addition, its possible mechanism is proposed.

Method for preparing alpha-acyloxy ketone compound

The invention discloses a method for preparing an alpha-acyloxy ketone compound. According to the invention, simple and easily available alcohol and carboxylic acid are taken as the raw materials, under mediation of NBS(N-bromo-succinimide) and DBU(1,8-diazabicyclo(5.4.0)undec-7-alkene), the alpha-acyloxy ketone is prepared by a one-pot reaction. The method has the advantages of mild reaction condition, simple and easily available raw materials, wide substrate adaptation scope, no requirement of rigorous reaction conditions such as any metal catalyst, peroxy compounds, low or high temperature and water-free and oxygen-free conditions, metal pollution is avoided; and the method also has the advantages of stable technical condition, simple and safe operation, and easy purifying of the product.