2723-07-1

Basic information

• Product Name: 5-Bromo-6β-hydroxy-20-oxo-5α-pregnan-3β-yl acetate
• CAS NO: 2723-07-1
• Molecular Weight: 455.432
• Mol File: 2723-07-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-Bromo-6β-hydroxy-20-oxo-5α-pregnan-3β-yl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Bromo-6β-hydroxy-20-oxo-5α-pregnan-3β-yl acetate(2723-07-1)
• EPA Substance Registry System: 5-Bromo-6β-hydroxy-20-oxo-5α-pregnan-3β-yl acetate(2723-07-1)

Safety Data

• Hazardous Substances Data: 2723-07-1(Hazardous Substances Data)

Upstream product

• 1778-02-5 Pregnenolone acetate 

Downstream Products

• 75220-37-0 19-oxo-deoxycorticosterone 
• 26360-40-7 3β-acetoxy-19-hydroxy-Δ5-pregnen-20-one 
• 6901-40-2 19,21-dihydroxypregn-4-ene-3,20-dione 21-acetate 
• 2394-23-2 19,21-dihydroxypregn-4-ene-3,20-dione 
• 4682-70-6 19-Nordeoxycorticosterone 
• 88378-35-2 19-oxo-11-deoxycorticosterone acetate 
• 596-63-4 19-Hydroxyprogesterone 
• 2205-86-9 6β,19-epoxypregn-4-en-3,20-dione 
• 5563-20-2 3β-hydroxy-5-bromo-6β,19-epoxy-5α-pregnan-20-one 

Relevant articles and documents

New Syntheses of 19,21-Dihydropregn-4-ene-3,20-dione, 21-Hydroxy-19-norpregn-4-ene-3,20-dione, and 11β,19,21-trihydroxypregn-4-ene-3,20-dione

19,21-Dihydroxypregn-4-ene-3,20-dione has been synthesized from 3β-acetoxypregn-5-en-20-one via the "hypoiodite reaction" , and Henbest acetoxylation at C-21; oxidation of the intermediate 21-monoacetate to 19-oxo derivative and alkaline cleavage gave 21-hydroxy-19-norpregn-4-ene-3,20-dione.A similar synthesis of 11β,19,21-trihydroxypregn-4-ene-3,20-dione from 3β-acetoxypregn-5-ene-11,20-dione proceeded through intermediates with the 11β-hydroxy function protected as its acetate.Unusual features mainly of conformational origin were observed in the presence of the 11β-acetoxy substituent; some were helpful to the synthesis, while others led to undesirable side reactions.