27339-25-9

Usage

Uses

Used in Pharmaceutical Industry:
3-(3,4-dimethoxyphenyl)-2-methyl-6-oxohexane-3-carbonitrile is used as an intermediate in the synthesis of pharmaceutical compounds for its potential medicinal properties. Its unique structure and functional groups contribute to the development of new drugs with therapeutic benefits.
Used in Agrochemical Industry:
3-(3,4-dimethoxyphenyl)-2-methyl-6-oxohexane-3-carbonitrile is used as a precursor in the production of agrochemicals, such as pesticides and herbicides, due to its potential biological activities against pests and weeds.
Used in Material Science:
3-(3,4-dimethoxyphenyl)-2-methyl-6-oxohexane-3-carbonitrile may have potential applications in the development of new materials, such as polymers and composites, owing to its unique structure and functional groups.
Used in Chemical Synthesis Processes:
3-(3,4-dimethoxyphenyl)-2-methyl-6-oxohexane-3-carbonitrile serves as a valuable building block for the synthesis of complex organic molecules and new chemical entities, contributing to the advancement of chemical synthesis processes and the discovery of novel compounds with potential applications in various industries.

InChI:InChI=1/C16H21NO3/c1-12(2)16(11-17,8-5-9-18)13-6-7-14(19-3)15(10-13)20-4/h6-7,9-10,12H,5,8H2,1-4H3

Upstream product

• 27339-24-8 2-(3,3-diethoxypropyl)-2-(prop-2-yl)-2-(3,4-dimethoxyphenyl)acetonitrile 
• 20850-49-1 2-(3,4-dimethoxyphenyl)-3-methylbutyronitrile 
• 93-17-4 3,4-dimethoxyphenylacetonitrile 

Downstream Products

• 103523-98-4 2-(3,4-Dimethoxy-phenyl)-2-isopropyl-5-[3-(2-methoxy-phenoxy)-propylamino]-pentanenitrile 
• 129975-51-5 2-(3,4-Dimethoxy-phenyl)-5-[4-(furan-2-carbonyl)-piperazin-1-yl]-2-isopropyl-pentanenitrile 
• 103523-99-5 2-(3,4-Dimethoxy-phenyl)-2-isopropyl-5-{[3-(2-methoxy-phenoxy)-propyl]-methyl-amino}-pentanenitrile 
• 23313-68-0 verapamil hydrochloride 
• 103523-37-1 Alpha-isopropyl-alpha-[3-[N-[2-(4-methoxyphenoxy)ethyl]amino]-propyl]-3,4-dimethoxyphenylacetonitrile 
• 120352-51-4 2-(3,4-Dimethoxy-phenyl)-2-isopropyl-5-{[3-(3-methoxy-phenoxy)-propyl]-methyl-amino}-pentanenitrile 
• 103523-40-6 2-(3,4-Dimethoxy-phenyl)-2-isopropyl-5-[2-(2-methoxy-phenoxy)-ethylamino]-pentanenitrile 
• 120352-25-2 2-(3,4-Dimethoxy-phenyl)-2-isopropyl-5-[3-(3-methoxy-phenoxy)-propylamino]-pentanenitrile 

Relevant academic research and scientific papers

PROCESS FOR PREPARING N-METHYL-3, 4-DIMETHOXYPHENYLETHYLAMINE

Provided are intermediates useful for the preparation of verapamil and methods for their preparation.

SOME NEW ANALOGUES OF VERAPAMIL AND MEPAMIL. SYNTHESIS AND BASIC PHARMACOLOGICAL PROPERTIES

Some new analogues of verapamil (Ia) and mepamil (Ib), calcium antagonists of arylkylamine type, were synthesized and screened for cardiovascular activities.The basic structure was modified a) on the phenyl ring, attached to the quaternary carbon, b) on the alkyl group, attached to the quaternary carbon and c) on the alkylamino group, attached in position 3 to the n-propyl fragment.Except of 2-(2-chlorophenyl)-2-isopropyl-5-(N-methylhomoveratrylamino)valeronitrile (VIa), all the synthesized compounds exhibited lower hypotensive activity, than the mother compound, verapamil.

Tetrahydroisoquinoline derivatives

Compounds of the formula STR1 wherein R1 and R2 and each independently --H or lower alkoxy; R3 and R4 are each independently lower alkyl; and R5 and R6 are each --OCH3, or together form --OCH2 O-- or --OCH2 CH2 O--, and pharmaceutically acceptable acid addition salts thereof are prepared by cyclizing, deoxygenating, coupling, or hydrogenating the intermediates disclosed herein.