27394-99-6

Basic information

• Product Name: N-(1-cyanoethyl)formamide
• Synonyms: N-(1-cyanoethyl)formamide;N-(1-Cyanethyl)formamid;2-(Formylamino)propanenitrile
• CAS NO: 27394-99-6
• Molecular Formula: C₄H₆N₂O
• Molecular Weight: 98.10324
• EINECS: 248-440-4
• Mol File: 27394-99-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 323.8 °C at 760 mmHg
• Flash Point: 149.6 °C
• Appearance: /
• Density: 1.038 g/cm³
• Vapor Pressure: 0.000256mmHg at 25°C
• Refractive Index: 1.426
• PKA: 13.59±0.23(Predicted)
• CAS DataBase Reference: N-(1-cyanoethyl)formamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1-cyanoethyl)formamide(27394-99-6)
• EPA Substance Registry System: N-(1-cyanoethyl)formamide(27394-99-6)

Safety Data

• Hazardous Substances Data: 27394-99-6(Hazardous Substances Data)

Usage

General Description

N-(1-cyanoethyl)formamide is a chemical compound with the molecular formula C4H6N2O, and it is classified as an amide. It is commonly used in the synthesis of pharmaceuticals, pesticides, and other organic compounds. This chemical is a colorless, flammable liquid with a faint odor, and it is soluble in water and most organic solvents. N-(1-cyanoethyl)formamide is also known for its potential health hazards, as it may cause irritation to the skin, eyes, and respiratory system upon exposure. It is important to handle and store this chemical with care and to follow proper safety protocols when working with it.

InChI:InChI=1/C4H6N2O/c1-4(2-5)6-3-7/h3-4H,1H3,(H,6,7)

Upstream product

• 77287-34-4 formamide 
• 78-97-7 2-hydroxy-propionitrile 
• 64-18-6 formic acid 
• 107-31-3 Methyl formate 
• 51806-98-5 2-aminopropanenitrile 

Downstream Products

• 71058-42-9 5-amino-6-methylpyridine-3,4-dicarbonitrile 
• 90330-09-9 7-amino-2,6-dimethyl-1,3-dioxo-1,3-dihydropyrrolo<3,4-c>pyridine 
• 90330-15-7 7-amino-2-methyl-(2,5-dioxo-1-methylpyrrolidin-3-yl)methyl-1,3-dihydropyrrolo<3,4-c>pyridine 
• 13162-05-5 n-vinylformamide 
• 114362-23-1 7-Acetamino-6-methyl-2-phenylpyrrolo<3,4-c>pyridine-1,3-dione 
• 14039-81-7 7-hydroxy-6-methyl-2-phenyl-pyrrolo[3,4-c]pyridine-1,3-dione 
• 71058-41-8 7-amino-6-methyl-1,3-dioxo-2-phenyl-1,3-dihydropyrrolo<3,4-c>pyridine 
• 90330-14-6 7-amino-6-(2,5-dioxo-1-phenylpyrrolidin-3-yl)methyl-1,3-dioxo-2-phenyl-1,3-dihydropyrrolo<3,4-c>pyridine 

Relevant articles and documents

N-Vinylformamide - Syntheses and Chemistry of a Multifunctional Monomer

N-Vinylformamide (VFA), the simplest member of the enamide group, is the key compound in the synthesis of linear cationic polymers with primary amino groups. In recent decades VFA has been the object of intensive research activity in industry and in universities with the aim of developing an economic method of synthesis. The various principles underlying the synthesis are described and the possibilities for their industrial realisation are discussed. From the large number of methods two variants have now been established as industrial production procedures at BASF and Mitsubishi Kasei Corp. (MKC). VFA is now available in tonne quantities in high purity. An overview of the versatile reaction possibilities of this multifunctional monomer and an extensive list of references are also given. The radical polymerisation to polyvinylformamides and their further reaction to polyvinylamines are not covered in this review.

New synthesis of alpha-N-formylaminonitriles, alpha-N-formylaminoamides and of alpha- and beta-amino acids

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