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Pyrrolo[1,2-a]pyrazine is a heterocyclic compound characterized by a fused ring structure that incorporates both a pyrrole and a pyrazine ring. This colorless liquid at room temperature is synthesized through various methods, such as the reaction of pyrrole with hydrazine. It is not only found naturally in some marine invertebrates but also identified as a component of tobacco smoke. Pyrrolo[1,2-a]pyrazine is recognized for its potential in the pharmaceutical industry as a building block for synthesizing a variety of bioactive compounds, including potential drug candidates. Its derivatives have demonstrated a spectrum of biological activities, such as antimicrobial, anti-inflammatory, and anticancer properties, which make them significant for ongoing research and development.

274-45-3

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274-45-3 Usage

Uses

Used in Pharmaceutical Industry:
Pyrrolo[1,2-a]pyrazine is used as a building block for the synthesis of various bioactive compounds due to its unique fused ring structure and potential in creating drug candidates with diverse therapeutic applications.
Used in Antimicrobial Applications:
Pyrrolo[1,2-a]pyrazine derivatives are used as antimicrobial agents for their ability to combat a range of microorganisms, providing a potential solution in the ongoing battle against antibiotic resistance.
Used in Anti-inflammatory Applications:
These derivatives are employed as anti-inflammatory agents, leveraging their biological activities to reduce inflammation and alleviate symptoms associated with various inflammatory conditions.
Used in Anticancer Applications:
Pyrrolo[1,2-a]pyrazine derivatives are used as anticancer agents, showing promise in targeting and inhibiting the growth of cancer cells, thereby contributing to cancer treatment and therapy development.

Check Digit Verification of cas no

The CAS Registry Mumber 274-45-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 2,7 and 4 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 274-45:
(5*2)+(4*7)+(3*4)+(2*4)+(1*5)=63
63 % 10 = 3
So 274-45-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H6N2/c1-2-7-6-8-3-5-9(7)4-1/h1-6H

274-45-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Pyrrolo[1,2-A]Pyrazine

1.2 Other means of identification

Product number -
Other names Pyrrolo<1,2-a>pyrazin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:274-45-3 SDS

274-45-3Relevant academic research and scientific papers

Pyrrolodiazines. 2. Structure and chemistry of pyrrolo[1,2-a]pyrazine and 1,3-dipolar cycloaddition of its azomethine ylides

Minguez, Jose M.,Castellote, Maria I.,Vaquero, Juan J.,Garcia-Navio, Jose L.,Alvarez-Builla, Julio,Castano, Obis,Andres, Jose L.

, p. 4655 - 4665 (1996)

A new synthesis of the pyrrolo[1,2-a]pyrazine system from pyrrole is described. In light of the ab initio calculations carried out on this heterocyclic system some of its basic chemistry was investigated and included electrophilic substitution, addition o

Cephalosporin derivatives

-

, (2008/06/13)

The present invention relates to novel cephalosporin derivatives or pharmaceutically acceptable non-toxic salts thereof useful as antibiotics and to processes for the preparation thereof. STR1 wherein: R1 is a hydrogen or an optionally halogen-

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