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2743-60-4

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2743-60-4 Usage

General Description

Ethyl L-leucinate is a chemical compound that belongs to the class of amino acid derivatives. It is comprised of an ethyl group and the amino acid L-leucine, which is one of the essential amino acids necessary for protein synthesis and maintaining muscle mass. Ethyl L-leucinate has been used in various industries, such as food and beverage, pharmaceuticals, and cosmetics, due to its potential flavor enhancing and antioxidant properties. It has also been studied for its potential anti-inflammatory and anti-cancer activities, making it a subject of interest for further research in medicinal and therapeutic applications.

Check Digit Verification of cas no

The CAS Registry Mumber 2743-60-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,7,4 and 3 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 2743-60:
(6*2)+(5*7)+(4*4)+(3*3)+(2*6)+(1*0)=84
84 % 10 = 4
So 2743-60-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H17NO2/c1-4-11-8(10)7(9)5-6(2)3/h6-7H,4-5,9H2,1-3H3/t7-/m0/s1

2743-60-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl (2S)-2-amino-4-methylpentanoate

1.2 Other means of identification

Product number -
Other names L-Leucine,ethyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2743-60-4 SDS

2743-60-4Relevant articles and documents

Research on solubility and bio-solubility of amino acids ionic liquids

Tian, Tian,Hu, Xiaoling,Guan, Ping,Ding, Xiaoqi

, p. 224 - 230 (2017)

Herein, the synthesis of L-(+)-α-(positive butyl)-leucine ethyl ester ionic liquids with anions based on bromide (Br?), terafluoroborate (BF4?) and hexafluorophosphate (PF6?) were presented. The structures and purities of these amino acids ionic liquids (AAILs) were characterized by 1H NMR and the determinations of water content. The interaction energies of AAILs-solvents/amino acids and dipole moment of AAILs were obtained through ab initio at MP2/6-311G?++(2d, p). The relationships between the solubility of AAILs and common solvents, molecular structure and the interaction energies of AAILs-solvents along with the influences of temperature and molecular structure on the bio-solubility of AAILs were discussed systematically. The results revealed that the solubility of the title AAILs increased firstly and then decreased with decreasing dielectric constant of solvent. With the dipole moment of AAILs and hydrogen bond interaction increasing, the solubility in polar solvents had an increasing trend. With the interaction energies of AAILs-solvents becoming bigger, AAILs can be easily dissolved in the solvents. The dissolution of amino acids in AAILs was largened with temperature increasing. Additional, the ease or difficulty of dissolution for amino acids in AAILs can be predicted by theoretical calculation. This prediction is consistent with the dissolution behavior of AAILs.

Stereoretentive N-Arylation of Amino Acid Esters with Cyclohexanones Utilizing a Continuous-Flow System

Ichitsuka, Tomohiro,Komatsuzaki, Shingo,Masuda, Koichiro,Koumura, Nagatoshi,Sato, Kazuhiko,Kobayashi, Shū

supporting information, p. 10844 - 10848 (2021/05/31)

The N-arylation of chiral amino acid esters with minimal racemization is a challenging transformation because of the sensitivity of the α-stereocenter. A versatile synthetic method was developed to prepare N-arylated amino acid esters using cyclohexanones as aryl sources under continuous-flow conditions. The designed flow system, which consists of a coil reactor and a packed-bed reactor containing a Pd(OH)2/C catalyst, efficiently afforded the desired N-arylated amino acids without significant racemization, accompanied by only small amounts of easily removable co-products (i. e., H2O and alkanes). The efficiency and robustness of this method allowed for the continuous synthesis of the desired product in very high yield and enantiopurity with high space-time yield (74.1 g L?1 h?1) and turnover frequency (5.9 h?1) for at least 3 days.

Stereospecific Synthesis of 3,4-Dihydro-2 H-naphtho-1,4-oxazin-2-ones by Unification of Benzoxepine-4-carboxylates with Chiral Amino Acid Ethyl Esters

Bhimapaka, China Raju,Kasagani, Veera Prasad,Kurma, Siva Hariprasad

supporting information, p. 2976 - 2983 (2020/03/23)

A novel and efficient stereocontrolled method has been developed for the preparation of chiral 3,4-dihydro-2H-naphtho[1,2-b][1,4]oxazin-2-ones by the reaction of benzoxepine-4-carboxylates with chiral amino acid ethyl esters for the first time. The chiral 3,4-dihydro-2H-naphtho-1,4-oxazinones have been achieved in one step by the formation of C-N, C-C, and C-O bonds.

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