2763-88-4

Upstream product

• 2525-62-4 Hexyl isocyanate 
• 3646-50-2 3-Amino-3-phenylpropionic acid 
• 111-26-2 hexan-1-amine 
• 201230-82-2 carbon monoxide 
• 62-53-3 aniline 
• 57-13-6 urea 
• 67-56-1 methanol 
• 100-46-9 benzylamine 
• 6343-54-0 N-benzylformamide 
• 124-38-9 carbon dioxide 
• 109-73-9 N-butylamine 
• 142-62-1 hexanoic acid 

Downstream Products

• 10264-30-9 N-hexyl-2-phenylacetamide 
• 15719-64-9 methylammonium carbonate 
• 74534-10-4 N-hexyldecanamide 
• 4773-75-5 N-hexylbenzamide 
• 67-56-1 methanol 
• 111-26-2 hexan-1-amine 

Relevant academic research and scientific papers

Full atom-efficiency transformation of wasted polycarbonates into epoxy thermosets and the catalyst-free degradation of the thermosets for environmental sustainability

We report two sustainable features in this work. The first feature is that we successfully applied wasted polycarbonate (WPC) as an epoxy curing agent for epoxy resins to prepare WPC-cured epoxy thermosets. The curing of WPC and epoxy is based on the reaction of a carbonate and an epoxide, which is proven by a model reaction of diphenyl carbonate (DPC) and glycidyl phenyl ether (GPE) in the presence of a catalytic amount of 4-dimethylaminopyridine (DMAP). The WPC-cured epoxy thermosets show comparable thermal properties to commercial-based, phenol novolac (PN)-cured epoxy thermosets. Interestingly, the films of WPC-cured epoxy thermosets are foldable, while those of PN-cured epoxy thermosets are brittle, demonstrating the advantage of using WPC as a curing agent over PN. Since the WPC was used directly without any digestion or pyrolysis process, the atomic efficiency is 100percent, making this WPC recycling strategy economically attractive. The second feature is that we successfully degraded the WPC-cured epoxy thermosets to phenoxy resins through a catalyst-free aminolysis process, that is, the products based on the WPC-cured epoxy thermosets are degradable when their lifespans are expired. The transformation of WPC into epoxy thermosets, along with the degradation of the epoxy thermosets, makes this work attractive for sustainability.

Iron-catalyzed reaction of urea with alcohols and amines: A safe alternative for the synthesis of primary carbamates

A general study of the iron-catalyzed reaction of urea with nucleophiles is here presented. The carbamoylation of alcohols allows for the synthesis of N-unsubstituted (primary) carbamates, including present drugs (Felbamate and Meprobamat, without the necessity to apply phosgene and related derivatives. Using amines as nucleophiles gave rise to the respective mono-and disubstituted ureas via selective transamidation reaction. These atom-economical transformations provide a direct and selective access to valuable compounds from cheap and readily available urea using a simple Lewis-acidic iron(Icatalyst.

Ruthenium-Catalyzed Urea Synthesis Using Methanol as the C1 Source

An unprecedented protocol for urea synthesis directly from methanol and amine was accomplished. The reaction is highly atom-economical, producing hydrogen as the sole byproduct. Commercially available ruthenium pincer complexes were used as catalysts. In addition, no additive, such as a base, oxidant, or hydrogen acceptor, was required. Furthermore, unsymmetrical urea derivatives were successfully obtained via a one-pot, two-step reaction.

Synthesis of urea derivatives from amines and CO2 in the absence of catalyst and solvent

Urea derivatives are obtained in mild to good yield from the reactions of primary aliphatic amines with CO2 in the absence of any catalysts, organic solvents or other additives. To optimize reaction conditions, experimental variables including temperature, pressure, the concentration of amine, reaction time etc. were studied. Satisfactory yields were obtained at the optimized conditions that are comparable to the presence of catalyst and solvent. The preliminary investigation of the reaction mechanism showed that alkyl ammonium alkyl carbamate was quickly formed as the intermediate, and then the final product was formed by the intramolecular dehydration.

A catalyst system for the reaction of carboxylic acids with aliphatic isocyanates

Catalysts have been found for the selective reaction of aliphatic isocyanates with carboxylic acids giving amides after carbon dioxide extrusion. Magnesium and calcium salts lead to a dramatic increase in reaction rates while improving the selectivity when sterically hindered isocyanates and/or carboxylic acids are used.

A novel ZrO2-SO42- supported palladium catalyst for syntheses of disubstituted ureas from amines by oxidative carbonylation

The syntheses of disubstituted ureas by carbonylation of a series of amines in the presence of a sulfate modified zirconia supported palladium catalyst was investigated at an initial total pressure of 4.0 MPa and 135°C. High conversions and yields were achieved for the synthesis of symmetric dialkylureas. This supported catalyst could also be easily separated and recovered after reaction.

NITROSATION OF N'-SUBSTITUTED 3- AND 4-UREIDOALKANOIC ACIDS

The nitrosation of N'-substituted 3- and 4-ureidoalkanoic acids, synthesized by the condensation of 3- and 4-aminoalkanoic acids with hexyl- and phenyl isocyanates, was studied under various conditions.The ratios of the obtained N- and N'-nitroso derivatives were established by PMR spectroscopy.