27657-11-0

Upstream product

• 6028-61-1 dipropyl trisulfide 
• 6493-73-8 dibenzyltrisulfide 
• 150-60-7 dibenzyl disulphide 
• 629-19-6 Dipropyl disulfide 
• 3012-37-1 benzyl thiocyanate 
• 599-91-7 propyl tosylate 
• 110-81-6 Diethyl disulfide 
• 2179-57-9 diallyl disulphide 
• 624-92-0 Dimethyldisulphide 
• 107-03-9 1-thiopropane 
• 27656-94-6 C₈H₁₀N₂S₂*ClH 

Relevant academic research and scientific papers

Phosphine-catalyzed disulfide metathesis

The reaction between disulfides and phosphines generates a reversible disulfide metathesis process. The Royal Society of Chemistry 2008.

NFSI-catalyzed S[sbnd]S bond exchange reaction for the synthesis of unsymmetrical disulfides

The metal-free S[sbnd]S bond exchange reaction of symmetrical disulfides catalyzed by NFSI is described. This novel protocol provides a facile and efficient approach to accessing important unsymmetrical disulfides. Furthermore, this strategy could also be utilized in the late-stage functionalization of amino acids, drugs, and natural products. The broad substrate scope, good functional group tolerance and easy accessibility of catalyst indicate that this strategy affords a green and practical complementary method to various unsymmetrical disulfides.

Method for NFSI-catalyzed synthesis of asymmetric disulphide derivatives

The invention belongs to the field of fine chemical engineering, and relates to a method for NFSI-catalytically synthesizing an asymmetric disulphide derivative, which comprises the following steps: NFSI. The symmetric disulfide A and the symmetric disulf

Microwave-assisted synthesis of asymmetric disulfides

Thiourea is very useful in the synthesis of asymmetric and symmetric disulfides. In this paper, we report an efficient, odorless, and one-pot procedure for the synthesis of benzyl alkyl disulfides by using the mixtures of thiourea, alkyl halides, and benzyl thiocyanates. The reaction was carried out in water with the assistance of microwaves, enabling a time-saving process. Optimal conditions were obtained as follows: benzyl thiocyanate (1.0 equiv.), thiourea (2.0 equiv.), and alkyl halide (1.2 equiv.) were reacted under microwave irradiation using K3PO4 as the base in water at 90 °C for 15 min. In most cases, the yields are higher than 80%. In this protocol, the substrates are readily available and their synthesis is much easier than the corresponding thiols. Moreover, it is environmentally and economically friendly.

Sulfur-Sulfur Bond Cleavage Processes. Selective Desulfurization of Trisulfides

The selectivity of sulfur removal in the desulfurization of trisulfides by tertiary phosphorus compounds has been investigated in detail.A mechanistic rationalization is proposed to account for central/terminal sulfur extrusion variation as a function of substrate structure and solvent polarity.