2778-84-9

Basic information

• Product Name: N-Ethyl-3-nitrophthalimide
• Synonyms: N-ETHYL-3-NITRO PHTHALIMIDE;2-ethyl-4-nitro-isoindole-1,3-dione;2-ethyl-4-nitroisoindole-1,3-dione;2-ethyl-4-nitro-isoindoline-1,3-quinone
• CAS NO: 2778-84-9
• Molecular Formula: C10H8N2O4
• Molecular Weight: 220.18
• Mol File: 2778-84-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 381 °C at 760 mmHg
• Flash Point: 184.2 °C
• Appearance: /
• Density: 1.448g/cm³
• Vapor Pressure: 5.24E-06mmHg at 25°C
• Refractive Index: 1.621
• CAS DataBase Reference: N-Ethyl-3-nitrophthalimide(CAS DataBase Reference)
• NIST Chemistry Reference: N-Ethyl-3-nitrophthalimide(2778-84-9)
• EPA Substance Registry System: N-Ethyl-3-nitrophthalimide(2778-84-9)

Safety Data

• Hazardous Substances Data: 2778-84-9(Hazardous Substances Data)

Usage

General Description

N-Ethyl-3-nitrophthalimide is a chemical compound with the molecular formula C12H9NO4. It is a nitroaromatic compound that is commonly used as a precursor in the synthesis of various pharmaceuticals and agrochemicals. N-Ethyl-3-nitrophthalimide is yellow in color and has a high melting point, making it suitable for use in organic synthesis. N-Ethyl-3-nitrophthalimide is also used as a reagent in the preparation of various organic compounds and is known for its ability to undergo a wide range of chemical reactions, making it a valuable building block in the production of many important substances.

InChI:InChI=1/C10H8N2O4/c1-2-11-9(13)6-4-3-5-7(12(15)16)8(6)10(11)14/h3-5H,2H2,1H3

Upstream product

• 74-96-4 ethyl bromide 
• 5329-95-3 potassium 3-nitrophthalimide 
• 603-11-2 3-nitrophthalic acid 
• 75-04-7 ethylamine 
• 603-62-3 4-nitro-1H-isoindole-1,3(2H)-dione 
• 75-03-6 ethyl iodide 

Relevant articles and documents

PHTHALIMIDE DERIVATIVES AS TRPA1 MODULATORS

The present invention provides TRPA (Transient Receptor Potential subfamily A) modulators. In particular, compounds described herein are useful for treating or preventing diseases, conditions and/or disorders modulated by TRPAl (Transient Receptor Potential subfamily A, member 1) modulators. Also provided herein are processes for preparing compounds described herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods for treating or preventing diseases, conditions and/or disorders modulated by TRPAl.

Characterization of Solute-Solvent Interaction at the Transition State by Thermodynamic and Quantum-mechanical Approaches. Reactions of Imidide Ions with Ethyl Iodide in Acetonitrile-Methanol

Single-ion enthalpies of transfer for transition-state anions of imidide ion plus ethyl iodide reactions have been determined in acetonitrile-methanol mixtures and have been partitioned into component enthalpies. ΔtHANMeOHPHYS and ΔtHANMeOHSl.Statistical analysis led to the empirical correlation incorporating nucleophiles and transition-state anions between specific interaction enthalpies, ΔtHANMeOHSl and the number of methanol molecules participating in the specific interaction with the anion.The molecular mechanistic origin of the specific interaction has been rationalized by introducing the cocept of 'effective atomic charge on the oxygen atom' which has been derived through semi-empirical MNDO/PM3 molecular orbital calculations.

Phthalimidyl-azo-m-acylamido-n-substituted aniline compounds and polyester fibers dyed therewith

Monoazo compounds containing a N-substituted-3- or 4-phthalimidyl diazo component and certain m-acylamido-N-substituted aniline residue coupling components produce bright scarlet to red shades on fibers of, for example, polyester, polyamide and cellulose esters, and exhibit improved dyeability properties and good to excellent fastness to light, high pH, sublimation and crocking.