2806-85-1

Usage

Uses

Used in Food and Beverage Industry:
3-ethoxypropionaldehyde is used as a flavoring agent for imparting a fruity or floral taste to food and beverages, enhancing the sensory experience of consumers.
Used in Perfumery:
3-ethoxypropionaldehyde is used as a fragrance ingredient in the production of perfumes, contributing to the creation of complex and appealing scents.
Used in Pharmaceutical Production:
3-ethoxypropionaldehyde is used as an intermediate in the synthesis of various pharmaceutical compounds, playing a crucial role in the development of new medications.
Used in Plastics Industry:
3-ethoxypropionaldehyde is utilized as an intermediate in the production of plastics, contributing to the manufacturing of diverse plastic materials with specific properties.
Used in Household Cleaning Products:
3-ethoxypropionaldehyde is used as a component in household cleaning products, helping to create effective formulations for cleaning and deodorizing purposes.
Used as a Solvent in Industrial Processes:
3-ethoxypropionaldehyde is employed as a solvent in various industrial processes, facilitating chemical reactions and material processing.
It is essential to handle 3-ethoxypropionaldehyde with care due to its potential to cause skin and eye irritation, and to follow safety protocols for storage and handling to ensure the well-being of workers and the environment.

InChI:InChI=1/C5H10O2/c1-2-7-5-3-4-6/h4H,2-3,5H2,1H3

Upstream product

• 64-17-5 ethanol 
• 107-02-8 acrolein 
• 141-52-6 sodium ethanolate 
• 7789-92-6 1,1,3-Triethoxy-propane 
• 12150-46-8 1,1'-bis-(diphenylphosphino)ferrocene 
• 109-92-2 ethyl vinyl ether 
• 201230-82-2 carbon monoxide 
• 83490-15-7 2-<2-(2-hydroxyethoxy)-ethyl>-1,3-dioxolane 
• 50-00-0 formaldehyd 
• 2141-62-0 3-(ethoxy)propionitrile 

Downstream Products

• 100910-92-7 1-ethoxy-pentan-3-ol 
• 18776-18-6 3-ethoxy-1-phenyl-1-propanol 
• 111-35-3 3-ethoxy-1-propanol 
• 4324-38-3 3-ethoxypropanoic acid 
• 131669-45-9 [(2R,3R)-3-(2-Ethoxy-ethyl)-oxiranyl]-methanol 
• 85-81-4 6-methoxy-8-nitroquinoline 
• 80912-11-4 8-methoxy-6-nitroquinoline 

Relevant academic research and scientific papers

Linear-selective hydroformylation of vinyl ether using Rh (acac)(2,2′-bis{(di[1H-indol-1-yl]phosphanyl)oxy}-1,1′-binaphthalene) – Possible way to synthesize 1,3-propanediol

Three bidentate phosphoramidite ligands were synthesized, characterized, and employed in Rh-catalyzed hydroformylation of vinyl ethers. The complex Rh(acac)(2,2′-bis{(di[1H-indol-1-yl]phosphanyl)oxy}-1,1′-binaphthalene} (acac = acetylacetone) (Rh-L4) was also synthesized and characterized. Rh-L4 showed good regioselectivity for the hydroformylation of vinyl ethers under mild reaction conditions: 2 MPa of syngas, 1:1 (H2/CO) substrate/catalyst molar ratio 1000:1, and 60 °C. The linear selectivity was up to 98%, and in most cases was about 80%, with no hydrogenation product formation observed, which could be a potential way to synthesize 1,3-propanediol. A mechanism study including density functional theory computational analysis showed that both Rh–H and CO insertion steps in the hydroformylation of vinyl ether were linear-preferred in our catalyst system.

Tetradentate phosphine ligand and preparation method thereof, hydroformylation catalyst and reaction method, and preparation method of 1, 3-propylene glycol

The invention provides a tetradentate phosphine ligand, a preparation method of the tetradentate phosphine ligand, a hydroformylation catalyst, a reaction method of the hydroformylation catalyst and apreparation method of 1, 3-propylene glycol, and belongs to the technical field of compound materials. The general formula of the tetradentate phosphine ligand is shown in the specification, whereinR1 is hydrogen or halogen, R2 is a nitrogen-containing heterocyclic ring or a complex of the tetradentate phosphine ligand and a rhodium complex, can be used for carrying out a hydroformylation catalytic reaction, and can be used for preparing 1, 3-propylene glycol.

Deprotection of acetals and ketals in a colloidal suspension generated by sodium tetrakis(3,5-trifluoromethylphenyl)borate in water

Deprotection of acetals and ketals can be achieved by using sodium tetrakis(3,5-trifluoromethylphenyl)borate (NaBArF4) as the catalyst in water at 30°C. For example, a quantitative conversion of 2-phenyl-1,3-dioxolane into benzaldehyde was accomplished within five minutes by using this sodium salt (0.1 mol%) in water. Georg Thieme Verlag Stuttgart.

PRECURSORS OF 3-ALKOXYALKANOLS AND PROCESSES FOR THE PREPARATION OF 3-ALKOXYALKANOLS

Processes for the preparation of 3-alkoxyalkanols useful as solvents for coating materials, photoresists, or the like.Specifcally,(1) a process which comprises reacting an α,β-unsaturated aldehyde with an alcohol in the presence of an acidic catalyst and subjecting the obtained product to hydrolysis and hydrogenation successively;(2) a process which comprises subjecting a reaction mixture obtained by the reaction of an α,β-unsaturated aldehyde with an alcohol and comprising the corresponding 1,1,3-trialkoxyalkane and 3-alkoxyalkanal to hydrolysis and hydrogenation at the same time;(3) a process which comprises recovering a 3-alkoxyalkanal through distillation as an azeotropic mixture thereof with water from a reaction solution obtained by the reaction of an alcohol with acid-containing acrolein or methacrolein prepared by the oxidation of propylene or isobutylene, and hydrogenating the recovered 3-alkoxyalkanal into the corresponding 3-alkoxyalkanol; and(4) a process which comprises bringing a gas produced by the oxidation of propylene or isobutylene Into contact with an alcohol, conducting the reaction of the gas with the alcohol to form the corresponding 1,1,3-trialkoxyalkane, and subjecting it to hydrolysis and hydrogenation.

Photochemical reactions of alkoxy-containing-alkyl phenylglyoxylates: Remote hydrogen abstraction

A series of alkoxy-containing-alkyl phenylglyoxylates have been synthesized and their photochemical reactions studied. The intention was to probe structural requirements for remote hydrogen abstraction. Products resulting from 1,10- and 1,11-hydrogen abstraction were isolated from the photochemical reactions of 4′-methoxybutyl phenylglyoxylate 3d and 5′-benzyloxypentyl phenylglyoxylate 3h respectively. Products resulting from Norrish Type II and intermolecular hydrogen abstraction reactions were also isolated. Triplet lifetimes of representative compounds were measured by laser flash photolysis.

Synthesis of 1,3-dibromopropane

A method for preparation of 1,3-dibromopropane from akrolein is proposed; it consists of alkylation of the starting compound, followed by catalytic reduction of the carbonyl group and bromination.

FACTORS AFFECTING REGIOSLECTIVITY IN THE RHODIUM-CATALYSED HYDROFORMYLATION OF VINYL ETHERS

The rhodium catalysed hydroformylation of vinyl ethers ROCH=CH2, where R is an alkyl, a benzyl or a phenyl group, has been investigated over the 20-100 deg C temperature range in the presence of Rh4(CO)12 or 2/PPh3 (1/6) as catalytic precursors.A mixture of 2-alkoxy-(or phenoxy)propanal (the α-isomer) and 3-alkoxy-(or phenoxy)propanal (the β-isomer) is obatined in good yield.The isomeric composition of the aldehydes depends on the structure of the substrate, on the catalytic precursor employed, and on the reaction temperature.The α-isomer predomines in all the cases, its predominance being greater (i) at low temperatures, (ii)in the presence of Rh4(CO)12 as catalyst precursor, and (iii) when a phenyl group is present in the β or γ position with respect to the double bond in the substrate.Electronic factors arising from the presence in the substrate of the oxygen atom and a phenyl group are more impotrant than the steric hindrance of tghe R group in detrmining the regioselectivity of the reaction.

Process for synthesis of acrylic acid precursors via hydroformylation of vinyl ether

A process is disclosed for the preparation of acrylic acid precursors by a hydroformylation process which comprises reacting a vinyl ether with carbon monoxide and hydrogen in the presence of a catalyst comprising a rhodium carbonyl compound and a phosphine ligand at a mild temperature and pressure until there is substantial formation of the intermediate 2- and 3-ethoxypropanals, followed by oxidation of said aldehydes and pyrolysis to said acrylic acid.

Derivatives of C-6 functionalized 4-heteroaldehydes. IV. Alcohol interchange via retro-Michael on acetals of 6-hydroxy-4-oxa-aldehydes: Synthesis of 2-alkoxyethyl-1,3-dioxolanes and derivatives

The alcohol interchange between 2--1,3-dioxolane 1 or 2--4-methyl-1,3-dioxolane (cis/trans mixture) 2, and methanol, ethanol, propanol or isopropanol, has been studied at the reflux temperature of mixtures. 1,1,3-Trialkoxy-propanes and 2-(2-alkoxyethyl)-1,3-dioxolanes were found when starting from 1 and 1,1,3-trialkoxypropanes, and 2-(2-alkoxyethyl)-4-methyl-1,3-dioxolanes (cis/trans mixtures, separated by glc) when starting from 2.The operativity of a retro-Michael reaction in the processes is proved; nevertheless, this does not occur when the reactions are carried out at room temperature.