111-35-3

Usage

Uses

Used in the Chemical Industry:
3-Ethoxy-1-propanol is used as a solvent for various applications in the chemical industry due to its ability to dissolve a wide range of substances. Its mild odor and relatively low density make it a suitable choice for dissolving compounds in a controlled environment.
Used in the Pharmaceutical Industry:
In the pharmaceutical industry, 3-Ethoxy-1-propanol is utilized as an intermediate in the synthesis of various drugs and active pharmaceutical ingredients. Its unique chemical structure allows it to participate in multiple chemical reactions, making it a valuable component in the development of new medications.
Used in the Cosmetics Industry:
3-Ethoxy-1-propanol is employed as a component in the formulation of cosmetics and personal care products. Its mild properties and ability to dissolve other ingredients make it a useful additive in the creation of lotions, creams, and other skincare products.
Used in the Cleaning Products Industry:
Due to its solvent properties, 3-Ethoxy-1-propanol is used in the formulation of cleaning products, such as detergents and degreasers. Its ability to dissolve a variety of substances makes it an effective ingredient for breaking down and removing dirt, grease, and stains.
Used in the Paints and Coatings Industry:
In the paints and coatings industry, 3-Ethoxy-1-propanol is utilized as a component in the formulation of various types of paint and coating solutions. Its solvent properties help to ensure proper mixing and application of the paint, as well as improving the overall performance of the final product.
Used in the Printing Industry:
3-Ethoxy-1-propanol is employed in the printing industry as a component in the formulation of inks and printing solutions. Its ability to dissolve other ingredients and improve the flow of the ink makes it a valuable additive in the production of high-quality printed materials.

Air & Water Reactions

Highly flammable. Water soluble.

Reactivity Profile

3-Ethoxy-1-propanol is an ethoxy-alcohol derivative. The ether is relatively unreactive. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert alcohols to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides.

Fire Hazard

3-Ethoxy-1-propanol is combustible.

InChI:InChI=1/C4H10O.C3H8O2/c1-3-5-4-2;1-3(5)2-4/h3-4H2,1-2H3;3-5H,2H2,1H3

Upstream product

• 503-30-0 trimethylene oxide 
• 64-17-5 ethanol 
• 2806-85-1 3-ethoxypropanal 
• 763-69-9 ethyl 3-ethoxypropionate 
• 75-03-6 ethyl iodide 
• 504-63-2 trimethyleneglycol 
• 107-02-8 acrolein 
• 141-52-6 sodium ethanolate 
• 627-30-5 1-chloro-3-hydroxypropane 
• 74-96-4 ethyl bromide 
• 37480-93-6 trimethylene glycol monosodium salt 
• 626-68-6 2-methyl-[1,3]dioxane 
• 86852-11-1 diethoxyltriphenylphosphorane 
• 67-56-1 methanol 

Downstream Products

• 36865-38-0 1-chloro-3-ethoxypropane 
• 36865-40-4 1-bromo-3-ethoxypropane 
• 91766-05-1 toluene-4-sulfonic acid 3-ethoxy-propyl ester 
• 5013-47-8 5-Jod-isophthalsaeure-bis-<3-aethoxy-propylester> 
• 52452-15-0 4-(3-Ethoxy-propoxy)-2-oxo-6-p-tolyl-cyclohex-3-enecarboxylic acid ethyl ester 
• 109-64-8 1,3-dibromo-propane 
• 10374-37-5 4-ethoxybutanoic acid 
• 5848-56-6 hydrocinnamyl ethyl ether 
• 90724-92-8 2,2-Dimethyl-5-ethoxy-pentanol 
• 90949-84-1 2,2-Dimethyl-5-ethoxy-pentannitril 
• 900156-46-9 C₁₄H₂₀O₅ 
• 279262-29-2 1-bromo-4-[3-(ethoxy)propoxy]benzene 
• 1056678-27-3 4-nitro-3-(3-ethoxy-propoxy)-benzoic acid methyl ester 
• 1193643-11-6 bis(3-ethoxypropyl) 5-(tetrahydropyran-2-yloxymethyl)isophthalate 

Relevant academic research and scientific papers

Dynamical Characterization in Aqueous Solutions of 3-Methoxy- and 3-Ethoxy-1-propanol by Ultrasonic Methods

3-Methoxy-1-propanol and 3-ethoxy-1-propanol were synthesized through potassium propoxide from 1,3-propanediol.Ultrasonic absorptions in their aqueous solutions were measured in the frequency range from 8.5 to 220 MHz as functions of their concentrations along with the sound velocity and density.In a solution of 3-ethoxy-1-propanol, a single relaxational absorption was observed; the cause was attributed to a perturbation of an equilibrium as AB A + B, where AB represents the solute-solvent complex, A the solute and B the solvent molecules.On the other hand, no relaxational absorption was observed in a 3-methoxy-1-propanol solution up to 4 mol dm-3.The thermodynamic and the kinetic parameters were evaluated for the abovementioned process from the concentration dependences of the ultrasonic parameters in a 3-ethoxy-1-propanol solution.From evidence concerning the appearance and disappearance of ultrasonic relaxational absorption and comparisons of the rate and thermodynamic constants in aqueous solutions of various alcohols, the alternation of the water structure affected by the addition of the solutes is discussed in connection with the solute structures.The methoxyl group was explicitly found to act as a water structure breaker and the ethoxyl group to do so slightly.

Tetradentate phosphine ligand and preparation method thereof, hydroformylation catalyst and reaction method, and preparation method of 1, 3-propylene glycol

The invention provides a tetradentate phosphine ligand, a preparation method of the tetradentate phosphine ligand, a hydroformylation catalyst, a reaction method of the hydroformylation catalyst and apreparation method of 1, 3-propylene glycol, and belongs to the technical field of compound materials. The general formula of the tetradentate phosphine ligand is shown in the specification, whereinR1 is hydrogen or halogen, R2 is a nitrogen-containing heterocyclic ring or a complex of the tetradentate phosphine ligand and a rhodium complex, can be used for carrying out a hydroformylation catalytic reaction, and can be used for preparing 1, 3-propylene glycol.

A formal anti-Markovnikov hydroalkoxylation of allylic alcohols with a ruthenium catalyst

Hydroalkoxylation of C-C double bonds was achieved through the use of a ruthenium catalyst. The reaction of allylic alcohols with nucleophilic alcohols was carried out in the presence of a ruthenium catalyst prepared by RuClH(CO)(PPh3)3 and 2,6-bis(n-butyliminomethyl)-4-(piperidin-1-yl)pyridine under mild reaction conditions to afford the corresponding γ-alkoxypropanols in good yield.

PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY LIQUID PHASE HYDROGENOLYSIS OF CYCLIC ACETALS OR CYCLIC KETALS

A liquid phase hydrogenolysis of acetal compounds such as cyclic acetals and cyclic ketals are fed to a reaction zone and reacted in the presence of a noble metal catalyst supported on a carbon or silica support to make hydroxy ether mono-hydrocarbons in high selectivity, without the necessity to use acidic co-catalysts such as phosphorus containing acids or stabilizers such as hydroquinone.

High purity 1,3-propanediol derivative solvent, process for producing the same, and use thereof

The present invention No. I is to obtain a high purity 3-alkoxy-1-propanol having the content of alcoholic impurities of not more than 0.3% by weight by allowing to react acrolein with a linear or branched alcohol having a carbon number of 1-4 using acrolein having the content of propionaldehyde of not more than 1% by weight as a raw material, a 3-alkoxy-1-propanol is produced by a hydrogenation reaction using hydrogen of a reaction mass under the presence of a catalyst, followed by recovering through a distillation of the 3-alkoxy-1-propanol having the content of alcoholic impurities of not more than 0.3% by weight from a crude solution in the hydrogenation reaction.

Synthesis and antiproliferative activity of alkylphosphocholines

Alkylphosphocholines (APC) with one or more methylene groups in the alkyl chain replaced by oxygen atoms or carbonyl groups, or both have been assembled modularly using ω-diols as central building blocks. Out of 25 new compounds of this kind, 11 were evaluated for their antiproliferative activity on four cell lines and compared with miltefosine to evaluate their hemolytic activity (HA) and cytotoxicity on non-tumoral cells (MT2), used as markers of adverse effects. Compound 13 was more active on cancer cell lines than on non-tumoral cells and the data were similar for MTT and thymidine incorporation assays. It had less HA than miltefosine. Compound 13 could therefore be a candidate for the preparation of compounds with higher cytotoxicity on cancer cells and lower general toxicity.

PRECURSORS OF 3-ALKOXYALKANOLS AND PROCESSES FOR THE PREPARATION OF 3-ALKOXYALKANOLS

Processes for the preparation of 3-alkoxyalkanols useful as solvents for coating materials, photoresists, or the like.Specifcally,(1) a process which comprises reacting an α,β-unsaturated aldehyde with an alcohol in the presence of an acidic catalyst and subjecting the obtained product to hydrolysis and hydrogenation successively;(2) a process which comprises subjecting a reaction mixture obtained by the reaction of an α,β-unsaturated aldehyde with an alcohol and comprising the corresponding 1,1,3-trialkoxyalkane and 3-alkoxyalkanal to hydrolysis and hydrogenation at the same time;(3) a process which comprises recovering a 3-alkoxyalkanal through distillation as an azeotropic mixture thereof with water from a reaction solution obtained by the reaction of an alcohol with acid-containing acrolein or methacrolein prepared by the oxidation of propylene or isobutylene, and hydrogenating the recovered 3-alkoxyalkanal into the corresponding 3-alkoxyalkanol; and(4) a process which comprises bringing a gas produced by the oxidation of propylene or isobutylene Into contact with an alcohol, conducting the reaction of the gas with the alcohol to form the corresponding 1,1,3-trialkoxyalkane, and subjecting it to hydrolysis and hydrogenation.

Synthesis of 1,3-dibromopropane

A method for preparation of 1,3-dibromopropane from akrolein is proposed; it consists of alkylation of the starting compound, followed by catalytic reduction of the carbonyl group and bromination.

Organic solvent soluble polyvalent metal alkoxy alkoxides

Organic solvent soluble alkoxides of magnesium, calcium, strontium, barium, scandium, yttrium and lanthanum are prepared by the reaction of these elements with alkoxy alcohols.

THE SYNTHETIC UTILITY OF DIOXYPHOSPHORANES IN ORGANIC SYNTHESIS

Diethoxytriphenylphosphorane, DTPP, prepared by reaction of triphenylphosphine and diethyl peroxide, is a "hydrolytically active" dioxyphosphorane which promotes mild and efficient cyclodehydration of diols to cyclic ethers in neutral media.Simple 1,2-, 1,4-, and 1,5-diols afford good yields of the cyclic ethers but 1,3-propanediol and 1,6-hexanediol give mainly 3-ethoxy-1-propanol and 6-ethoxy-1-hexanol, respectively, with DTPP.Tri- and tetra-substituted 1,2-diols afford the relatively stable 1,3,2-dioxaphospholanes in the presence of DTPP and the reaction conditions dictate whether epoxides, ketones, or allylic alcohols are obtained.