28224-74-0Relevant articles and documents
Synthesis of new analogues of salacinol containing a pendant hydroxymethyl group as potential glycosidase inhibitors
Nasi, Ravindranath,Pinto, B. Mario
, p. 2305 - 2311 (2007/10/03)
The synthesis of new analogues of the naturally occurring glycosidase inhibitor, salacinol, and its ammonium analogue, ghavamiol is described. These analogues contain an additional hydroxymethyl group at C-1, which was intended to form additional polar co
Synthesis of amphiphilic polyhydroxylated pyrrolidines as potential glycosidase inhibitors
Esposito, Annamaria,Falorni, Massimo,Taddei, Maurizio
, p. 6543 - 6546 (2007/10/03)
Several polyhydroxylated pyrrolidines with an aliphatic long chain on the ring nitrogen were prepared starting from D-mannitol. An amphiphilic bis- azasugar scaffold has been also prepared. These products behave as cationic surfactants and show a promising anti HIV-1 activity.