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1-<2-(4-Nitrophenyl)acetyl>-4-<3-(trifluoromethyl)phenyl>piperazine is a complex organic compound with the molecular formula C21H20F3N3O3. It features a piperazine core, which is a heterocyclic amine containing two nitrogen atoms in a six-membered ring. The compound has a 4-nitrophenyl group attached to the acetyl group at position 2 and a 3-trifluoromethylphenyl group at position 4. The presence of the nitro group and trifluoromethyl group contributes to its unique chemical properties, making it a potentially interesting molecule for various applications in the fields of pharmaceuticals, agrochemicals, or materials science.

2823-65-6

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2823-65-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2823-65-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,8,2 and 3 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2823-65:
(6*2)+(5*8)+(4*2)+(3*3)+(2*6)+(1*5)=86
86 % 10 = 6
So 2823-65-6 is a valid CAS Registry Number.

2823-65-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[2-(4-Nitrophenyl)acetyl]-4-[3-(trifluoromethyl)phenyl]piperazine

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

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More Details:2823-65-6 SDS

2823-65-6Upstream product

2823-65-6Relevant academic research and scientific papers

Preparation and biodistribution of -[125I]Iodo-4-aminophenyl)ethyl]-4-[3-(trifluoromethyl)phenyl]piperazine and -[125I]Iodo-4-azidophenyl)ethyl]-4-[3-(trifluoromethyl)phenyl]piperazine

Chumpradit,Kung,Billings,Guo,Wu,Shih

, p. 543 - 547 (2007/10/02)

The iodinated analogue of 1-[2-(4-aminophenyl)ethyl]-4-[3-(trifluoromethyl)phenyl]piperazine (PAPP), IPAPP (4), and the corresponding azido compound azido-IPAPP (5) were synthesized. The corresponding no-carrier-added 125I (T( 1/2 ) = 60 days, 35-60 keV) labeled compounds were also prepared. High specific binding was observed from in vitro binding studies using rat brain tissue preparation; K(i) = 20 and 17.5 nM against [3H]-5-HT. In vivo biodistribution studies in rats showed that azido-[125I]IPAPP passed through intact blood-brain barrier and localized in the brain. Ex vivo autoradiography of rat brain sections exhibited a diffuse uptake pattern, which may be due to specific and nonspecific binding. The results indicate that IPAPP and azido-IPAPP may not be suitable to image the serotonin receptor in the brain.

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